Evidence map›Paper›PMID 40019677›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Valuing health-related quality of life: an EQ-5D-5L value set for Morocco.

Asmaa Azizi, Amal Boutib, Doha Achak, Fredrick Dermawan Purba, Fanni Rencz, Elmadani Saad, Abderraouf Hilali, Samir Ahid, Chakib Nejjari, Elly A Stolk and 3 more

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ordinal relationship of composite time trade-off and discrete choice experiment preference data.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  3. The EQ-5D-5L valuation study in Nigeria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Asmaa AziziLaboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Amal Boutib *Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Doha Achak *Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Fredrick Dermawan PurbaFaculty of Psychology, Universitas Padjadjaran, Jatinangor, Indonesia.
Fanni RenczDepartment of Health Policy, Corvinus University of Budapest, Budapest, Hungary.
Elmadani SaadLaboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Abderraouf HilaliLaboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Samir AhidEuromed Research Center, Euromed University of Fez (UEMF), Fez, Morocco.
Chakib NejjariEuromed Research Center, Euromed University of Fez (UEMF), Fez, Morocco.
Elly A StolkEuroQol Research Foundation, Marten Meesweg 107, Rotterdam, The Netherlands.
Bram RoudijkEuroQol Research Foundation, Marten Meesweg 107, Rotterdam, The Netherlands.
Ibtissam Youlyouz-MarfakLaboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, 26000, Settat, Morocco.
Abdelghafour MarfakEuromed Research Center, Euromed University of Fez (UEMF), Fez, Morocco. ab.marfak@gmail.com.ORCID http://orcid.org/0000-0002-4212-8438

Funding

EuroQol Research Foundation 1411-VS
6 · The paper itself

Abstract

purposeThere is a growing interest in Health Technology Assessment (HTA) in Morocco. A national EQ-5D-5L value set would allow for the computation of Quality Adjusted Life Years (QALYs) in economic evaluations of healthcare interventions to support decision-making. This study aimed to develop a Moroccan EQ-5D-5L value set based on data from a representative sample of the Moroccan adult general population.

methodsA Moroccan representative sample of adults was recruited using stratified quota sampling based on gender, age category, and place of residence. Data were collected between November 2022 and December 2023 using the international EuroQol valuation protocol, EQ-VT version 2.6.1. This protocol includes two elicitation techniques: the composite time trade-off (cTTO) and the discrete choice experiment (DCE). cTTO and DCE data were modeled using a heteroskedastic Tobit model and a conditional logit model, respectively. In addition, these models were combined using a hybrid model.

resultsA total of 976 respondents were included in the final analysis. The hybrid heteroskedastic model was considered the preferred model. The predicted utility values ranged from -1.492 for the worst health state (55555) to 1 for full health (11111), where the two mildest impaired states (11211 and 21111) had a utility value of 0.979. Pain/discomfort had the largest effect on health utility values, followed by anxiety/depression, mobility, self-care and usual activities.

conclusionMorocco is the third country in the Middle East and North Africa (MENA) region with an EQ-5D-5L value set. This study supports the use of EQ-5D-5L data for healthcare decision-making in the Moroccan context.

Indexed as

Health StatusQuality-Adjusted Life YearsQuality of LifeAdolescentAdultAgedFemaleHumansMaleMiddle AgedMoroccoSurveys and QuestionnairesTechnology Assessment, BiomedicalYoung AdultcTTODCEEQ-5D-5LEQ-VTUtilityValue set

Identifiers

PMID40019677
PMCPMC12119695

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.