Evidence map›Paper›PMID 40019644›Full record

ArticleAnnals of intensive care2025

The trajectory of sleep after critical illness: a 24-month follow-up study.

Mario Henríquez-Beltrán, Iván D Benítez, Rafaela Vaca, Sally Santisteve, Maria Aguilà, Anna Vila, Olga Minguez, Carlos Rodríguez-Muñoz, Anna Galán-González, Sulamita Carvalho-Brugger and 13 more

Abstract read
In one paragraph

Article in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Mario Henríquez-Beltrán *Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Iván D Benítez *Translational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Rafaela VacaTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Sally SantisteveTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Maria AguilàTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Anna VilaTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Olga MinguezTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Carlos Rodríguez-MuñozTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Anna Galán-GonzálezTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Sulamita Carvalho-BruggerIntensive Care Department, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Paula GonzálezIntensive Care Department, Hospital Universitari Santa Maria, Lleida, Spain.
Paula RodríguezIntensive Care Department, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Jesús CaballeroIntensive Care Department, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Carme BarberàIntensive Care Department, Hospital Universitari Santa Maria, Lleida, Spain.
Gerard TorresTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Gonzalo LabarcaDepartment of Respiratory Diseases, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Mar Malla-BanyeresTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Anna Moncusí-MoixTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Antoni TorresCIBER of Respiratory Diseases (CIBERES), Institute of Health Carlos III, Madrid, Spain.
David de Gonzalo-CalvoTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Ferran BarbéTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Jessica GonzálezTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain.
Adriano D S TargaTranslational Research in Respiratory Medicine, Hospital Universitari Arnau de Vilanova-Santa Maria, Biomedical Research Institute of Lleida (IRBLleida), Rovira Roure, 80, 25198, Lleida, Spain. atarga@irblleida.cat.ORCID http://orcid.org/0000-0002-7577-7661

Funding

Instituto de Salud Carlos III CP20/00041Instituto de Salud Carlos III CP23/00095Instituto de Salud Carlos III FI23/00253Instituto de Salud Carlos III PI22/00216Sociedad Española de Neumología y Cirugía Torácica SEPAR/1555-2024
6 · The paper itself

Abstract

backgroundSurvivors of critical illness endure long-lasting physical and mental challenges. Despite the persistence of poor sleep quality in a considerable proportion of patients at the 12-month follow-up, studies with assessments exceeding this period are limited. We aimed to investigate the trajectory of sleep over the 24 months following critical illness.

methodsObservational, prospective study. Patients diagnosed with SARS-CoV-2 infection were recruited during the intensive care unit stay. Evaluations of sleep (Pittsburgh Sleep Quality Index [PSQI]), mental health (Hospital Anxiety and Depression Scale [HADS]), quality of life (12-item Short Form Survey [SF-12]), and other factors were performed in the short-term, and at 12 and 24 months after hospital discharge. Good sleep quality was defined as a PSQI score of ≤ 5. Minimal clinically important improvement (MCII) was defined as a decrease of ≥ 4 points in the PSQI score between the short-term assessment and the 24-month follow-up.

resultsThe cohort included 196 patients (69.9% males), with a median [p

conclusionsOur findings reveal that a subset of critical illness survivors requires up to 24 months after the acute phase to fully restore their sleep quality, while a significant proportion does not experience a clinically significant improvement in sleep quality over this period. These distinct sleep trajectories are strongly correlated with mental health status, highlighting the importance of addressing sleep alongside mental health within the framework of post-intensive care syndrome.

Indexed as

Critical survivorsMental healthPittsburgh sleep quality indexSARS-CoV-2Sleep

Identifiers

PMID40019644
PMCPMC11871202

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