Evidence map›Paper›PMID 40019587›Full record

ArticleEJNMMI research2025

Molecular imaging in hypertrophic cardiomyopathy: an exploratory study with 2-[

Maria João Ferreira, Patrícia Marques-Alves, Rodolfo Silva, Andreia Gomes, Antero Abrunhosa, Miguel Castelo-Branco, Wael Jaber, Lino Gonçalves

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In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria João Ferreira *Universidade de Coimbra, Coimbra, Portugal.
Patrícia Marques-Alves *Centro Académico e Clínico de Coimbra, Coimbra, Portugal. pat.marques.alves@gmail.com.ORCID http://orcid.org/0000-0002-2639-4058
Rodolfo SilvaUniversidade de Coimbra, Coimbra, Portugal.
Andreia GomesInstituto Ciências Nucleares Aplicadas à Saúde (ICNAS), Coimbra, Portugal.
Antero AbrunhosaUniversidade de Coimbra, Coimbra, Portugal.
Miguel Castelo-BrancoUniversidade de Coimbra, Coimbra, Portugal.
Wael JaberCleveland Clinic, Cleveland, Ohio, United States of America.
Lino GonçalvesUniversidade de Coimbra, Coimbra, Portugal.

Funding

Sociedade Portuguesa de Cardiologia Bolsa João Porto 2020
6 · The paper itself

Abstract

backgroundHypertrophic Cardiomyopathy (HCM), a genetic disorder with diverse phenotypes, is associated with risks of heart failure and sudden cardiac death. While the condition involves multiple pathological pathways, including myocardial inflammation, increased workload, myocyte disarray, apoptosis, and fibrosis, the role of molecular imaging via PET-CT remains unexplored in this context. This study aimed to investigate the relationship between myocardial metabolism and perfusion using PET-CT in patients with non-obstructive HCM (NOHCM).

resultsMyocardial perfusion and metabolism were assessed using PET-CT with [

conclusionIn patients with NOHCM, PET-CT imaging provides valuable insights into myocardial metabolism and fibrosis, which are closely associated with myocardial hypertrophy, left ventricular dysfunction, and the risk of sudden cardiac death.

Indexed as

Cardiac PET-CT imagingHypertrophic cardiomyopathyMyocardial metabolism and perfusionSudden cardiac death

Identifiers

PMID40019587
PMCPMC11871154

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.