SynthesisSurgical endoscopy2025
Quantification of indocyanine green fluorescence angiography in colorectal surgery: a systematic review of the literature.
Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of indocyanine green fluorescence imaging in colorectal cancer: a systematic review and meta-analysis of randomized controlled trials.International journal of colorectal disease · 2025Pooled it
- Quantification of indocyanine green fluorescence angiography in colorectal surgery: a systematic review of the literature.Surgical endoscopy · 2025Pooled it
- Patient's weight-based indocyanine green dose for fluorescence angiography with led imaging system in left-sided colorectal resections.Surgical endoscopy · 2026Article
- Prevention, Recognition, and Management of Anastomotic Leakage and Pelvic Sepsis After Rectal Cancer Surgery: A Structured Narrative Review.Journal of clinical medicine · 2026Review
- A novel real-time assessment of intestinal perfusion with dual imaging using ICG fluorescence and capillaroscopy in colorectal surgery.Langenbeck's archives of surgery · 2026Article
- Perioperative splanchnic perfusion variation around colorectal surgery using both indocyanine green spectrophotometry and fluorescence angiography.Surgical endoscopy · 2026Article
- Real-time indocyanine green perfusion assessment demonstrates regional vascularity and loss of perfusion in the anterior cruciate ligament during knee arthroscopy.Journal of experimental orthopaedics · 2026Article
- Fluorescence-guided surgery in colorectal cancer: current evidence, quantitative advances, and future perspectives.Annals of coloproctology · 2026Review
- Improved Quantification of ICG Perfusion Through Motion Compensation in Fluorescence-Guided Surgery.Diagnostics (Basel, Switzerland) · 2026Article
- Unusual cause of small bowel obstruction in a liver transplant recipient: a case report and focused literature review.Frontiers in surgery · 2026Article
- Indocyanine green fluorescence angiography in laparoscopic sigmoid and rectal cancer surgery: no reduction in anastomotic leakage but a lower incidence of anastomotic strictures. A prospective single-center study.Frontiers in surgery · 2026Article
- Beyond fluorescence intensity: a Minimum acquisition and reporting standard and emerging technologies for colorectal indocyanine green fluorescence angiography studies.Frontiers in surgery · 2026Article
- The evaluation of cognitive workload associated with indocyanine green fluorescence angiography in colorectal surgery.Surgical endoscopy · 2026Article
- Seeing beyond white light: fluorescence for safer laparoscopic cholecystectomy.Frontiers in surgery · 2026Review
- AUGUR-AI: a real-time artificial intelligence interpreter for indocyanine green fluorescence angiography in colorectal surgery.Surgical endoscopy · 2025Article
- Evaluating the Efficacy of Indocyanine Green Fluorescence Angiography in Lower Extremity Injuries: A Systematic Review.Strategies in trauma and limb reconstructionReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndocyanine green fluorescence angiography (ICGFA) during colorectal surgery associates with reduced post-operative anastomotic complication rates. Because its interpretation is subjective, quantification has been proposed to address inter-user variability. This study reviews the published literature regarding ICGFA quantification during colorectal surgery with a focus on impactful clinical deployment.
methodsA systematic review was performed of English language publications regarding clinical studies of ICGFA quantification in colorectal surgery in PubMed, Scopus, Web of Science and Cochrane Library on 29th August 2024, updated to 18th November 2024, following PRISMA guidelines. Newcastle Ottawa scale (NOS) was used to assess quality.
resultsA total of 1428 studies were screened with 22 studies (1469 patients) selected. There was significant heterogeneity of ICGFA methodology, quantification methods and parameter selection and only three studies were NOS "high" quality. Extracorporeal application was most common. Four studies (154 patients) conducted real-time ICGFA analyses (others were post hoc) and four utilised artificial intelligence methods. Eleven studies only included patients undergoing left-sided resection (six focusing specifically on rectal resections). Only one study employed the quantification method to guide intra-operative decision-making regarding colonic transection. Twenty-six different perfusion parameters were assessed, with time from injection to visible fluorescence and maximum intensity the most commonly (but not only) correlated parameters regarding anastomotic complication (n = 18). Other grounding correlates were tissue oxygenation (n = 3, two with hyperspectral imagery), metabolites (n = 2) and surgeon interpretation (n = 5).
conclusionQuantification of the ICGFA signal for colorectal surgery is feasible but has so far seen limited academic advancement beyond feasibility.
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