Evidence map›Paper›PMID 40019548›Full record

Observational studyNeuroradiology2025

Multiphase CTA vs. MRA collateral map for predicting functional outcomes after acute ischemic stroke.

Sang Bong Lee, Hong Gee Roh, Taek-Jun Lee, Yoo Sung Jeon, Hee Jong Ki, Jin Woo Choi, Na Il Shin, Ho Hyun Nam, Jin Tae Kwak, Ji Sung Lee and 2 more

Abstract readObservational StudyComparative Study
PubMed Publisher
In one paragraph

Observational study in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sang Bong LeeDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Hong Gee RohKonkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
Taek-Jun LeeDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Yoo Sung JeonKonkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
Hee Jong KiDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Jin Woo ChoiKonkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.
Na Il ShinDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Ho Hyun NamDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea.
Jin Tae KwakDeepClue Inc., Daejeon, Republic of Korea.
Ji Sung LeeClinical Research Center, Asan Institute for Life Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jeong Jin ParkKonkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea. medicalstory@gmail.com.
Hyun Jeong KimDaejeon St. Mary'S Hospital, College of Medicine, the Catholic University of Korea, Seoul, Republic of Korea. mskendy429@gmail.com.

Funding

The National Research Foundation of Korea RS-2023-00248375The National Research Foundation of Korea RS-2023-00266130
6 · The paper itself

Abstract

purposeTo compare the prognostic abilities of multiphase CT angiography (mCTA) and multiphase MR angiography (MRA) collateral map in acute anterior circulation ischemic stroke.

methodsThis secondary analysis of a prospective observational study included data from participants with acute ischemic stroke due to steno-occlusion of the internal carotid artery and/or middle cerebral artery within 8 h of symptom onset between January 1, 2016, and March 31, 2021. The intermethod agreement of the collateral scores (CSs) from mCTA and the collateral perfusion scores (CPSs) from the MRA collateral map was analyzed. Multiple logistic regression analyses were conducted to determine the prognostic value of mCTA and MRA collateral maps.

results169 participants (106 men and 63 women, mean age 69 years ± 13) were included. The agreement between the CSs of mCTA and the CPSs of the MRA collateral map (weighted kappa = 0.44, 95% confidence interval [CI]: 0.37-0.52) of 168 participants was moderate. Younger age (Odds ratio [OR], 0.51; 95% CI, 0.34-0.76; p = 0.001), lower baseline NIHSS scores (OR, 0.89; 95% CI, 0.81-0.99; p = 0.024), CPS 4 (OR, 36.66; 95% CI, 1.79-750.29; p = 0.019) and CPS 5 (OR, 144.10; 95% CI, 1.11-18788.93; p = 0.046) on the MRA collateral map, and successful reperfusion (OR, 9.63; 95% CI, 3.00-30.94; p < 0.001) were independently associated with favorable functional outcomes.

conclusionsOnly the MRA collateral map demonstrated clinical prognostic value in acute anterior circulation ischemic stroke patients, demonstrating the superiority of the MRA collateral map over mCTA in collateral assessment.

Indexed as

Cerebral AngiographyCollateral CirculationComputed Tomography AngiographyIschemic StrokeMagnetic Resonance AngiographyAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesCerebral infarctionCerebrovascular circulationCT angiographyMagnetic resonance angiographyStroke

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.