Evidence map›Paper›PMID 40019545›Full record

ArticleAnnals of hematology2025

The impact of various types of α-thalassemia on perinatal complications and pregnancy outcomes in pregnant women.

Yi Li, Yuanyuan Feng, Yiyun Wei, Jing Huang, Hui Chen, Changqiang Wei, Kaiyi Wei, Lihong Pang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi LiDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Yuanyuan FengDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Yiyun WeiDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Jing HuangDepartment of Obstetrics and Gynecology, The Maternity and Child Health Hospital of Guangxi Zhuang Autonomous Regin, Nanning, Guangxi, 530002, China.
Hui ChenDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Changqiang WeiDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Kaiyi WeiDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Lihong PangDepartment of Prenatal Diagnosis and Genetic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China. panglihong@sr.gxmu.edu.cn.

Funding

Clinical Research Climbing Program of the First Affiliated Hospital of Guangxi Medical University YYZS2022006National Natural Science Foundation of China 81960281
6 · The paper itself

Abstract

This study aims to investigate the adverse effects of different types of α-thalassemia on pregnant women and their differences, so as to provide reference for the prevention and monitoring of perinatal complications in different types of α-thalassemia pregnancy. The observation group comprised 1371 singleton pregnant women with α-thalassemia, control group comprised 680 non-thalassemia singleton pregnancies during the same period. The thalassemia genotypes of the observation group were tallied and categorized based on their respective genotypes within the group. The hemoglobin in the experimental group was lower than control group. The incidences of electrocardiographic abnormality, abnormal liver function, hypertensive disorders, gestational diabetes mellitus and thyroid disorders during pregnancy were higher in the observation group than in the control group. The incidences of preterm labor, caesarean section and postpartum hemorrhage were all higher in the observation group than in the control group. The delivery weight and neonatal hemoglobin in the observation group were lower than those in the control group. Pregnant women with α-thalassemia have more pregnancy and delivery complications than those without α-thalassemia, they should receive more frequent and standardized prenatal examination, so as to find and correct abnormal indicators in time.

Indexed as

alpha-ThalassemiaPregnancy Complications, HematologicPregnancy OutcomeAdultFemaleHumansInfant, NewbornPostpartum HemorrhagePregnancyYoung AdultComplicationsHemoglobinPregnancyPregnancy outcomeΑ-thalassemia

Identifiers

PMID40019545
PMCPMC12031830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.