ReviewHNO2025
[Current hypotheses on the development of chronic otitis media with effusion in childhood].
Review in HNO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Targeting Eustachian Tube Microenvironment: Probiotic Surfactant Utilization for Antimicrobial Peptide Secretion to Prevent Otitis Media.Probiotics and antimicrobial proteins · 2026Review
- Beyond the nose: hearing status in 70 patients with congenital choanal atresia.European journal of pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic otitis media with effusion (COME) has a major impact on a child's physical and social development. Socioeconomic risk factors as well as new insights gained with modern laboratory technology and large demographic studies of COME in Central Europe are discussed. In total, 428 articles from the past 8 years on PubMed were reviewed as well as current guidelines of German- and English-speaking countries on COME in children. Problems of many original studies include small patient numbers and bias. In addition, a clear distinction between acute otitis media and COME is often missing. Microbiomic profiles and biofilms seem to play a major role in COME. Established theories on the multifactorial origin of COME are mostly supported by new studies, including new insights into immunological and nutritional risk factors. In addition, the socioeconomic background of a child with COME must not be underestimated, even in first-world countries.
Indexed as
Identifiers
40019513What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.