SynthesisArchives of gynecology and obstetrics2025
Efficacy and safety of acupuncture-related therapies in symptomatic endometriosis: a systematic review and network meta-analysis.
Synthesis in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Acupuncture combined with Chinese herbal medicine versus Chinese herbal medicine alone to improve clinical efficacy in treating endometriosis-associated pain: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Curcumin Alleviates Endometriosis in Sexually Mature Female Mice by Targeting PKA and Inhibiting De Novo Estrogen Synthesis.Biomedicines · 2026Article
- Study on the clinical effect of warm acupuncture in the treatment of simple obesity complicated with dyslipidemia (spleen deficiency and dampness obstruction type) and insulin resistance.American journal of translational research · 2026Article
- Comparative Effectiveness of Non-Pharmacological Interventions for Pain and Quality of Life in Women with Endometriosis: A Systematic Review and Network Meta-Analysis.Journal of pain research · 2026Review
- Article
- Concerns on classification, statistical methods, and interpretation in NMA on acupuncture for endometriosis.Archives of gynecology and obstetrics · 2025Article
- Endometriosis: new insights and opportunities for relief of symptoms.Biology of reproduction · 2025Review
- Bridging tradition and innovation: electroacupuncture's impact on premature ovarian insufficiency.Frontiers in endocrinology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveTo compare the effectiveness and safety of different acupuncture-related therapies combined with pharmacotherapies for treating symptomatic endometriosis.
methodsA pre-defined search strategy was conducted across eight databases (Chinese Biomedical Literature Service System, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, China Science and Technology Journal Database, PubMed, Embase, Cochrane Library, and Web of Science) from inception to May 1, 2023. The included studies were evaluated for methodological quality using the Cochrane risk of bias assessment tool. The surface under the cumulative ranking (SUCRA) was applied to rank the acupuncture-related therapies for each outcome.
resultsTwenty-three randomized controlled trials (RCTs) involving one thousand five hundred forty-five patients were included in the network meta-analysis. Ear electroacupuncture (SUCRA = 83.0%), needle warming moxibustion with Modified Neiyi Zhitong Formula (SUCRA = 80.6%), and auricular needle-embedding (SUCRA = 79.6%) demonstrated a statistically significant reduction in comprehensive symptoms compared to the control group. Studies have shown that body electroacupuncture (OR = 4.33, 95% CI 1.20-15.61), acupoint catgut (OR = 4.32, 95% CI 1.08-17.25), and auricular needle-embedding (OR = 7.56, 95% CI 1.89-30.28) are statistically significantly more effective than conventional treatment.
conclusionThe results of this analysis suggest that acupuncture-related therapies are effective in managing symptomatic endometriosis. Further high-quality randomized controlled trials are warranted to explore their efficacy and safety in greater depth.
trial registrationOur study protocol was registered with the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY); registration number: INPLASY202380077.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.