Evidence map›Paper›PMID 40019351›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Identifying Key Properties That Drive Redox Mediator Activity in Lactiplantibacillus Plantarum.

Benjamin T Blackburn, Robyn A C Alba, Vladimir O Porokhin, Rong Cai, Arden Hatch, Soha Hassoun, Caroline M Ajo-Franklin, Emily Mevers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Electrochemistry as a Tool for Redox-Based Bio-Information Processing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin T BlackburnDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia, USA.
Robyn A C AlbaDepartments of BioScience and Chemical, Biomolecular Engineering, Rice University, Houston, Texas, USA.
Vladimir O PorokhinDepartment of Computer Science, Tufts University, Medford, Massachusetts, USA.
Rong CaiDepartments of BioScience and Chemical, Biomolecular Engineering, Rice University, Houston, Texas, USA.
Arden HatchDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia, USA.
Soha HassounDepartment of Computer Science, Tufts University, Medford, Massachusetts, USA.
Caroline M Ajo-FranklinDepartments of BioScience and Chemical, Biomolecular Engineering, Rice University, Houston, Texas, USA.
Emily MeversDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia, USA.ORCID 0000-0001-7986-5610

Funding

Army Research Office W911NF-22-1-0239
6 · The paper itself

Abstract

Lactiplantibacillus plantarum is known to utilize exogenous small molecule quinone mediators to perform extracellular electron transfer (EET), allowing it to produce a detectable current in a bioelectrochemical system (BES). Utilization of quinone mediators by L. plantarum requires a type-II NADH dehydrogenase (Ndh2); however, structural variations in the core of 1,4-naphthoquinone EET mediators have shown to yield significantly different current outputs. Herein, we assembled a library of 40 quinone-based EET mediators to probe the important physicochemical properties and biochemical interactions responsible for Ndh2-dependent EET in L. plantarum. The library was designed with inspiration from naturally occurring metabolites, and assembly was focused on structural modifications that diversified polarity, reduction potential, and predicted free energy of binding to Ndh2 (ΔG

Indexed as

Lactiplantibacillus plantarumNADH DehydrogenaseElectron TransportOxidation-ReductionNADH DehydrogenaseBiosensingExtracellular electron transferLactiplantibacillus plantarumNdh2Quinone

Identifiers

PMID40019351
PMCPMC12051747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.