Evidence map›Paper›PMID 40019334›Full record

ReviewCancer reports (Hoboken, N.J.)2025

CT-Imaging Manifestations and Diagnostic Insights in Pulmonary Intravascular Large B-Cell Lymphoma: A Case Series and Literature Review.

Xinyi Gou, Yinli Zhang, Yuan Li, Libao Hu, Jin Cheng, Nan Hong

Abstract readCase ReportsReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinyi GouDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Yinli ZhangDepartment of Pathology, Peking University People's Hospital, Beijing, China.
Yuan LiDepartment of Nuclear Medicine, Peking University People's Hospital, Beijing, China.
Libao HuDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Jin ChengDepartment of Radiology, Peking University People's Hospital, Beijing, China.ORCID 0000-0002-1199-1351
Nan HongDepartment of Radiology, Peking University People's Hospital, Beijing, China.

Funding

Natural Science Foundation of Beijing Municipality L242061Peking University People's Hospital Scientific Research and Development Funds RDJ2022-08
6 · The paper itself

Abstract

backgroundIntravascular large B-cell lymphoma (IVLBCL) is a rare and aggressive subtype of non-Hodgkin lymphoma. Although autopsy findings have revealed that IVLBCL often involves the lungs, its clinical features and imaging manifestations have rarely been reported. This study aimed to explore the pulmonary imaging manifestations of three patients with pulmonary IVLBCL. CASE: We retrospectively reviewed the clinical data and chest computed tomography (CT) images of three patients diagnosed with pulmonary IVLBCL between January 2010 and July 2023 in our hospital. In this case series, three patients (2 males and 1 female, aged 51-65 years) presented with a variety of symptoms. Laboratory tests revealed elevated lactate dehydrogenase levels in all three individuals. Chest CT scans revealed bilateral ground-glass opacities (GGOs) in the lungs in all cases. Although previous case reports have often depicted GGOs as ill-defined, two of the three cases manifested multiple well-circumscribed GGOs. Two cases underwent fluorodeoxyglucose positron emission tomography (FDG) PET/CT scans, which showed increased FDG uptake in pulmonary lesions (SUVmax values of 1.9 and 1.7, respectively).

conclusionChest CT images of patients with pulmonary IVLBCL mainly manifested as bilateral GGOs of the lungs, with ill-defined GGO infiltrations being more common. FDG PET/CT demonstrates high diagnostic sensitivity for detecting pulmonary involvement in IVLBCL. Even when chest CT scans reveal no visible abnormalities, FDG PET/CT can detect enhanced metabolic uptake in areas with lesions for certain patients.

Indexed as

Lung NeoplasmsLymphoma, Large B-Cell, DiffuseVascular NeoplasmsAgedAntineoplastic Combined Chemotherapy ProtocolsFemaleFluorodeoxyglucose F18HumansLungMaleMiddle AgedPositron Emission Tomography Computed TomographyRetrospective StudiesTomography, X-Ray ComputedFluorodeoxyglucose F18chest computed tomographyground‐glass opacitiesintravascular large B‐cell lymphoma

Identifiers

PMID40019334
PMCPMC11869564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.