Evidence map›Paper›PMID 40019281›Full record

ArticleJournal of chemical information and modeling2025

SynTemp: Efficient Extraction of Graph-Based Reaction Rules from Large-Scale Reaction Databases.

Tieu-Long Phan, Klaus Weinbauer, Marcos E González Laffitte, Yingjie Pan, Daniel Merkle, Jakob L Andersen, Rolf Fagerberg, Christoph Flamm, Peter F Stadler

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Extension of partial atom-to-atom maps: uniqueness and algorithms.Algorithms for molecular biology : AMB · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tieu-Long PhanBioinformatics Group, Department of Computer Science &Interdisciplinary Center for Bioinformatics &School for Embedded and Composite Artificial Intelligence (SECAI), Leipzig University, Härtelstraße 16-18, D-04107 Leipzig, Germany.ORCID 0000-0002-3532-2064
Klaus WeinbauerBioinformatics Group, Department of Computer Science &Interdisciplinary Center for Bioinformatics &School for Embedded and Composite Artificial Intelligence (SECAI), Leipzig University, Härtelstraße 16-18, D-04107 Leipzig, Germany.
Marcos E González LaffitteBioinformatics Group, Department of Computer Science &Interdisciplinary Center for Bioinformatics &School for Embedded and Composite Artificial Intelligence (SECAI), Leipzig University, Härtelstraße 16-18, D-04107 Leipzig, Germany.
Yingjie PanDepartment of Mathematics and Computer Science, University of Southern Denmark, DK-5230 Odense M, Denmark.
Daniel MerkleDepartment of Mathematics and Computer Science, University of Southern Denmark, DK-5230 Odense M, Denmark.ORCID 0000-0001-7792-375X
Jakob L AndersenDepartment of Mathematics and Computer Science, University of Southern Denmark, DK-5230 Odense M, Denmark.
Rolf FagerbergDepartment of Mathematics and Computer Science, University of Southern Denmark, DK-5230 Odense M, Denmark.ORCID 0000-0003-1004-3314
Christoph FlammDepartment of Theoretical Chemistry, University of Vienna, Währingerstraße 17, A-1090 Vienna, Austria.
Peter F StadlerBioinformatics Group, Department of Computer Science &Interdisciplinary Center for Bioinformatics &School for Embedded and Composite Artificial Intelligence (SECAI), Leipzig University, Härtelstraße 16-18, D-04107 Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reaction templates are graphs that represent the reaction center as well as the surrounding context in order to specify salient features of chemical reactions. They are subgraphs of

Indexed as

CheminformaticsDatabases, ChemicalCluster Analysis

Identifiers

PMID40019281
PMCPMC11938280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.