Evidence map›Paper›PMID 40018672›Full record

ReviewFrontiers in microbiology2025

Applying nanopore sequencing in the etiological diagnosis of bloodstream infection.

Yiqun Liao, Junjie Gong, Xiaoling Wang, Puwen Chen, Qinxing Chi, Xiaohong Chen

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiqun LiaoDepartment of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Junjie GongDepartment of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Xiaoling WangDepartment of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Puwen ChenThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, China.
Qinxing ChiThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, China.
Xiaohong ChenDepartment of Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bloodstream infection (BSI) is a systemic infectious disease that can lead to shock, disseminated intravascular coagulation, multiorgan failure, and even death. Blood culture is considered the gold standard for the etiological diagnosis of BSI; however, blood culture is time-consuming and has a low positivity rate, which has limited its utility for early and rapid clinical diagnosis. Nanopore sequencing technology (NST), a third-generation sequencing method, offers rapid detection, real-time single-molecule sequencing, and ultra-long reads. These features enable the prompt detection of pathogens and the analysis of drug-resistant genes and genomic characteristics, thereby optimizing the clinical diagnosis and treatment of BSI. In this article, we summarize the application of NST in the etiological diagnosis of BSI.

Indexed as

bloodstream infectionetiological diagnosishigh-throughput sequencingnanopore sequencingwhole genome sequencing

Identifiers

PMID40018672
PMCPMC11865208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.