Characterization of upper airway airflow dynamics in young adults with isolated Robin sequence: An exploratory investigation.

Maria Noel Marzano-Rodrigues, Sergio Henrique Kiemle Trindade, Ivy Kiemle Trindade-Suedam

Abstract read

In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Patient-Specific Computational Fluid Dynamics Modeling of Airway Collapse in Infants With Robin Sequence.International journal for numerical methods in biomedical engineering · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Noel Marzano-RodriguesSchool of Medicine, Life and Health Science Institute, Catholic University of Pelotas, Pelotas, Brazil.

Sergio Henrique Kiemle TrindadeLaboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo and Bauru School of Medicine, University of São Paulo, Brazil.

Ivy Kiemle Trindade-SuedamLaboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo and Bauru School of Dentistry, University of São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impaired upper airway dimension in adults with Isolated Robin Sequence (IRS) can alter airflow dynamics, increasing the risk of pharyngeal collapse and the onset of obstructive sleep apnea. This study aimed to characterize the upper airways of six young adults (20.83 ± 6.40 years) with IRS, using computational fluid dynamics. Upper airways of six patients were reconstructed using 3D segmentation, generating unstructured hybrid meshes with ≥4 million tetrahedral elements. Flow simulations at 15 l/min were solved using the realizable k-ε model and the finite volume method. Morphophysiological variables assessed were: total airway volumes, minimal cross-sectional areas, average pressure, velocity magnitude, wall shear stress, turbulent kinetic energy (k) production, and resistance. Airway volume corresponded to 29.32 ± 4.65 cm³ and minimal cross-sectional area was 1.00 ± 0.55 cm

Indexed as

3D imagingAirway obstructionFluid dynamicsRobin sequence

Identifiers

PMID40018666

DOI10.1016/j.jobcr.2025.01.009

PMCPMC11867517

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.