Evidence map›Paper›PMID 40018647›Full record

ArticleChemical & biomedical imaging2025

Recombinant-Chemosynthetic Biosensors for Probing Cell Surface Signaling of Red Blood Cells and Other Cells.

Sithurandi Ubeysinghe, Chloe O Sebilleau, Waruna Thotamune, Chathuri Rajarathna, Samuel Azibere, Mithila Tennakoon, John L Payton, Randy S Sprague, R Scott Martin, Steven J Sucheck and 1 more

Abstract read
In one paragraph

Article in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sithurandi UbeysingheDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Chloe O SebilleauDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.
Waruna ThotamuneDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Chathuri RajarathnaDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Samuel AzibereDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.ORCID https://orcid.org/0000-0003-1302-7643
Mithila TennakoonDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
John L PaytonCollege of Sciences, University of Findlay, Findlay, Ohio 45840, United States.
Randy S SpragueDepartment of Pharmacology and Physiology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, United States.
R Scott MartinDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Steven J SucheckDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.ORCID https://orcid.org/0000-0003-0082-3827
Ajith KarunarathneDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.ORCID https://orcid.org/0000-0003-3136-2015

Funding

Optical control of endogenous G protein Coupled Receptor and G Protein Signaling.R01GM140191 · NIGMS · UNIVERSITY OF TOLEDO · PI KARUNARATHNE, WELIVITIYA KANKANAMLAGE AJITH · 2021 to 2023
$1.0M
NIGMS NIH HHS R01 GM140191
6 · The paper itself

Abstract

The complex signaling mechanisms in red blood cells (RBCs) enable them to adapt to physiological stresses such as exposure to low O

Identifiers

PMID40018647
PMCPMC11863169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.