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ArticleCureus2025

Translation, Reliability and Validity of the Greek Version of the 5-D Itch Scale in People With Chronic Kidney Disease Receiving Haemodialysis.

Anastasia Liossatou, Aspasia Panagiotou, Dimitris Papageorgiou, Victoria Alikari, Georgia Gerogianni, Electra Lykiardopoulou, John D Stathoulis, Chara Tzavara, Marlyn J Mayo, Sofia Zyga

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anastasia LiossatouFaculty of Health Sciences, Department of Nursing, University of Peloponnese, Tripoli, GRC.
Aspasia PanagiotouFaculty of Health Sciences, Department of Nursing, University of Peloponnese, Tripoli, GRC.
Dimitris PapageorgiouFaculty of Health Sciences, Department of Nursing, University of Peloponnese, Tripoli, GRC.
Victoria AlikariDepartment of Nursing, University of West Attica, Athens, GRC.
Georgia GerogianniDepartment of Nursing, University of West Attica, Athens, GRC.
Electra LykiardopoulouDepartment of Digital Media and Communication, Ionian University, Kefalonia, GRC.
John D StathoulisBiomedical Engineering, Sparta General Hospital, Sparta, GRC.
Chara TzavaraBiostatistics, National and Kapodistrian University of Athens, Medical School, Athens, GRC.
Marlyn J MayoDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
Sofia ZygaFaculty of Health Sciences, Department of Nursing, University of Peloponnese, Tripoli, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease-associated pruritus (CKD-aP) is a condition that causes significant distress to people undergoing haemodialysis (HD). It significantly impacts individuals' sleep habits, everyday activities, social interactions, mental health and overall quality of life. A number of tools have been developed to evaluate the severity of pruritus. The 5-D itch scale is one of the most widely used tools for assessing various aspects of pruritus. In Greece, there is no validated and culturally adapted tool to assess pruritus in individuals with CKD receiving HD. Hence, this study aimed to evaluate the reliability and validity of the Greek version of the 5-D itch scale. MATERIALS AND

methodsThe English version of the 5-D itch scale was translated into the Greek language according to international guidelines and was cross-culturally adapted in people with CKD on HD (Ν = 120). The intraclass correlation coefficient was used to assess the reliability of the instrument after the test-retest procedure (n = 30). Confirmatory factor analysis was conducted in order to test how well the 5-D itch scale one-factor model fits the data. Internal consistency reliability was determined by the calculation of Cronbach's alpha coefficient (n = 120). Convergent validity was tested through the correlation with the Kidney Disease Quality of Life Instrument Short-Form (KDQOL-SF) scale and the visual analogue scale. Statistical significance was set at p < 0.05. Analyses were conducted using IBM SPSS Statistics for Windows, version 26.0 (released 2019, IBM Corp., Armonk, NY).

resultsThe sample consisted of 120 people with CKD receiving HD (60.0% males, n = 72), with a mean age of 65.7 years (SD ±13 years), of whom 80 individuals reported CKD-aP. Regarding confirmatory factor analysis, this solution had a good model fit (χ2/df = 1.93; root mean square error of approximation (RMSEA) = 0.03; comparative fit index (CFI) = 0.92; Tucker Lewis index (TLI) = 0.93 and standardized root mean square residual (SRMR) = 0.05). The intraclass correlation coefficients were significant (p < 0.001) in all items and over 0.85. Cronbach's alpha for the 5-D itch scale total score was 0.75, indicating good reliability. The reliability index had minor changes after removing its items; thus, no item needed to be removed from the scale. The correlation of the 5-D itch scale with the KDQOL-SF (p = 0.002) indicates the good convergent validity of the scale.

conclusionThe Greek version of the 5-D itch scale is an instrument with good reliability and validity, possessing the potential to be utilised by healthcare professionals for the purpose of the assessment of CKD-aP among Greek-speaking people undergoing HD.

Indexed as

5-d itch scalechronic kidney diseasechronic kidney disease-associated prurituscross-cultural adaptationhaemodialysisitchingnephrology nursingreliabilitytranslationvalidity

Identifiers

PMID40018505
PMCPMC11866260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.