Evidence map›Paper›PMID 40018501›Full record

ArticleCureus2025

Unexpected Neurological Deterioration Following Occipitocervical Fusion Surgery: A Case Report.

Takane Nakagawa, Hiroshi Takahashi, Kousei Miura, Toru Funayama, Masao Koda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takane NakagawaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Hiroshi TakahashiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Kousei MiuraDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Toru FunayamaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.
Masao KodaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occipitocervical posterior decompression and fusion (O-C fusion) surgery is occasionally required for treating high cervical myelopathy due to atlantoaxial subluxation. The advance of the instrumentation systems has led to favorable clinical outcomes following O-C fusion surgery. However, the rate of perioperative complications in O-C fusion surgery is relatively high, including instrumentation failure, respiratory complications, and dysphagia. Here we report a rare case involving an unexpected deterioration of myelopathy following O-C fusion surgery. A 49-year-old male was transported to our hospital by ambulance with left-sided upper and lower limb paralysis. At the initial visit, a neurological examination revealed left upper limb weakness (manual muscle testing (MMT) grade 2). X-ray and CT revealed severe atlantoaxial subluxation due to os odontoideum, while MRI revealed significant spinal cord compression at the C2 level. On the diagnosis of acute exacerbation of high cervical myelopathy, an O-C2 posterior decompression and fusion surgery, including C1 laminectomy, was performed. Postoperatively, the patient exhibited a deterioration in right-sided upper limb paralysis (MMT grade 2), despite proper implant placement confirmed by CT. During two weeks postoperatively, there was no improvement in the right-sided upper limb paralysis, and bilateral deep sensory impairment worsened. Follow-up X-rays revealed a progressive decrease in the O-C2 angle, and dynamic X-ray imaging demonstrated a recurrence of instability at the O-C2 level. On the diagnosis of the instrumentation failure, a revision surgery was performed three weeks after the primary surgery. Intraoperative findings revealed instability at the C2 screw head and loosening of the set screw on the C2 screw head. To achieve a more secure fixation, we extended the fusion to C4 with a triple rod connection. Following the revision surgery, his myelopathy and paralysis gradually improved. At the final follow-up, six months after surgery, X-rays showed that O-C2 was firmly stabilized. In conclusion, screw head fixation close to the O-C rod bending site may result in unexpected instrumentation failure in O-C fusion surgery.

Indexed as

atlantoaxial subluxationhigh cervical myelopathyinstrumentation failureoccipitocervial fusion surgeryos odontoideumtriple rod

Identifiers

PMID40018501
PMCPMC11867050

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.