Evidence map›Paper›PMID 40018494›Full record

ArticleCureus2025

Herpes Simplex Virus Type 1-Induced Cervicitis Without Vulvar Lesions Mimicking Cervical Cancer in a Healthy Woman.

Akina Nigi, Tomohisa Kihira, Akinobu Hayashi, Tadashi Yabana, Hiroyuki Tanaka

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akina NigiObstetrics and Gynecology, Japanese Red Cross Ise Hospital, Ise, JPN.
Tomohisa KihiraObstetrics and Gynecology, Japanese Red Cross Ise Hospital, Ise, JPN.
Akinobu HayashiPathology, Japanese Red Cross Ise Hospital, Ise, JPN.
Tadashi YabanaPathology, Japanese Red Cross Ise Hospital, Ise, JPN.
Hiroyuki TanakaInfectious Diseases, Japanese Red Cross Ise Hospital, Ise, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genital herpes, caused by herpes simplex virus (HSV) types 1 and 2, is a common sexually transmitted disease typically presenting with genital lesions and discomfort. However, a cervical mass without vulvar lesions is a rare manifestation of the disease, often leading to diagnostic confusion with cervical cancer. This report highlights a unique case of HSV type 1-induced cervical swelling in the absence of vulvar lesions, confirmed through pathological diagnosis. To our knowledge, this is the first documented instance where HSV type 1-induced cervical mass was confirmed through pathological diagnosis. Magnetic resonance imaging, pathological analysis, and immunohistochemistry were key in distinguishing the condition from malignancy. This case underscores the importance of considering HSV infection in differential diagnoses for a cervical mass and provides critical insights for the accurate diagnosis and management of HSV-related cervicitis.

Indexed as

cervical cancercervical swellingcervicitisgenital infectionherpes simplex virushsvperinatal complication

Identifiers

PMID40018494
PMCPMC11867049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.