Evidence map›Paper›PMID 40018487›Full record

ArticleCureus2025

A Rare Case of Bilateral Xanthogranulomatous Pyelonephritis Secondary to Candida albicans.

Prakrati Yadav, Ji Yoon Park, Aijaz Parisa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fungal pyelonephritis (JFMS open reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Prakrati YadavInternal Medicine, Charleston Area Medical Center, Charleston, USA.
Ji Yoon ParkInternal Medicine, Charleston Area Medical Center, Charleston, USA.
Aijaz ParisaInternal Medicine, Charleston Area Medical Center, Charleston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic inflammatory renal disease typically caused by bacterial infections. We hereby report a rare case of bilateral XGP secondary to Candida albicans in a 31-year-old female with multiple autoimmune disorders. The patient presented with nonspecific abdominal discomfort, painful urination, and generalized weakness. Computed tomography (CT) of the abdomen revealed bilateral hydronephrosis, renal enlargement, and chronic changes consistent with XGP. Despite aggressive antifungal therapy, her renal function progressively deteriorated, ultimately leading to multi-organ failure and death. This case underscores the importance of maintaining a high index of suspicion for XGP in immunocompromised patients to facilitate early diagnosis and potentially improve outcomes. Additionally, it highlights the unique diagnostic challenge posed by C. albicans as a causative pathogen in XGP, emphasizing the need to consider fungal infections in the differential diagnosis to avoid delays in treatment.

Indexed as

candida albicansfungal infectionnephrectomyrenal enlargementxanthogranulomatous pyelonephritis

Identifiers

PMID40018487
PMCPMC11867148

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.