Evidence map›Paper›PMID 40018474›Full record

ArticleCureus2025

Virus-Induced Hypercoagulable State: A Mythical Cause for Cerebral Venous Sinus Thrombosis in an Adult Male.

Nithish Nanda Palanisamy, Nandha Kumar Selvam, Sentamilselvan Vijayan, Vijayakumaran Ethiraju

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nithish Nanda PalanisamyInternal Medicine, Coimbatore Medical College, Coimbatore, IND.
Nandha Kumar SelvamEmergency Medicine, Kovai Medical Center and Hospital, Coimbatore, IND.
Sentamilselvan VijayanEmergency Medicine, Kovai Medical Center and Hospital, Coimbatore, IND.
Vijayakumaran EthirajuRadiology, Kovai Medical Center and Hospital, Coimbatore, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chickenpox is a common childhood disease that presents with erythematous rashes. In adults, varicella can cause complications with significant morbidity. Cerebral venous sinus thrombosis (CVST) is a life-threatening condition if not promptly treated. Here, we report a rare case of CVST complicating primary varicella-zoster virus infection. We present a case of a 34-year-old immunocompetent male with diffuse maculopapular rash and acute neurological deficit. Magnetic resonance venography revealed acute thrombosis involving the superior sagittal sinus, straight sinus, right transverse sinus, and confluence of sinuses. While arterial infarcts are well-known, venous thrombosis is less documented, particularly during active infection. The underlying mechanism may involve a hypercoagulable state induced by the infection or direct viral invasion of the venous endothelium, leading to endothelial damage and subsequent thrombosis.

Indexed as

acquired protein s deficiencycerebral venous sinus thrombosis (cvst)emergency medical servicemr venogramvaricella zoster virus infection

Identifiers

PMID40018474
PMCPMC11866259

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.