Evidence map›Paper›PMID 40018451›Full record

ArticlePrecision chemistry2025

Salt Metathesis: An Ultimate Click Reaction.

Christopher M Butch, Patrick C Hillesheim, Arsalan Mirjafari

Abstract read
In one paragraph

Article in Precision chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher M ButchDepartment of Chemistry, State University of New York at Oswego, Oswego, New York 13126, United States.
Patrick C HillesheimDepartment of Chemistry and Physics, Ave Maria University, Ave Maria, Florida 34142, United States.ORCID https://orcid.org/0000-0002-9567-4002
Arsalan MirjafariDepartment of Chemistry, State University of New York at Oswego, Oswego, New York 13126, United States.ORCID https://orcid.org/0000-0002-5502-0602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this Comment, we suggest salt metathesis (or ion exchange) as an ultimate click reaction, extending click chemistry principles beyond covalent bonds to ionic interactions. These universal and robust reactions, which nature utilizes in marine organisms' biomineralization processes, proceed spontaneously under mild conditions with minimal waste, embodying the core principles of click philosophy. This perspective expands the traditional scope of click chemistry and opens new opportunities in synthetic accessibility across organic, inorganic, and materials science spaces.

Identifiers

PMID40018451
PMCPMC11863168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.