Evidence map›Paper›PMID 40018377›Full record

ReviewCardiovascular therapeutics2025

Frontiers and Hotspot Evolution of NLRP3 Inflammasome in Myocardial Infarction Research: A Bibliometric Analysis From 2013 to 2024.

Jin-Wen Wu, Qi Lan, Ding-Shan Zhang, Yu-Hong Jian, Lin Yu, Rui Hao, Ping Liu, Gang Luo, Ming-Tai Chen, Meng-Nan Liu

Abstract readReview
In one paragraph

Review in Cardiovascular therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. The role of IL-6 in atherosclerosis: a narrative review.Frontiers in cardiovascular medicine · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jin-Wen WuDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-7875-1598
Qi LanDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0004-6061-6138
Ding-Shan ZhangDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0008-8544-9574
Yu-Hong JianDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0003-5119-8483
Lin YuDepartment of Orthopaedics, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.ORCID https://orcid.org/0009-0001-6181-4492
Rui HaoSchool of Nursing, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0009-0001-3998-8197
Ping LiuDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0001-7085-2098
Gang LuoDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-0487-2311
Ming-Tai ChenDepartment of Cardiovascular Disease, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0003-4579-5559
Meng-Nan LiuDepartment of Cardiovascular Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0001-9991-642X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an essential role in myocardial infarction (MI) development. Up to now, no bibliometric analyses of NLRP3 in MI have been performed. Publications related to NLRP3 in MI from 1 January 2013 to 20 August 2024 were extracted from the Web of Science Core Collection (WoSCC). HistCite Pro, CiteSpace, VOSviewer, Scimago Graphica, and bibliometric online analysis program were used for bibliometric analysis and visualization. The impact of publications was assessed using the total global citation score (TGCS). A total of 324 articles (284 articles and 40 reviews) were included. China has published the most in this field, followed by the United States. Harbin Medical University was the leading institution for research related to NLRP3 in MI. Professor Abbate A. from the United States has made significant achievements in this field.

Indexed as

Biomedical ResearchCardiologyInflammasomesMyocardial InfarctionMyocardiumNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsBibliometricsHumansPeriodicals as TopicSignal TransductionInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanbibliometric analysismyocardial infarctionmyocardial ischemia–reperfusion injuryNLRP3

Identifiers

PMID40018377
PMCPMC11865457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.