ArticleFrontiers in neuroscience2025
Prenatal maternal life adversity impacts on learning and memory in offspring: implication to transgenerational epigenetic inheritance.
Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Maternal Social Support Reshapes the Offspring Brain Transcriptome to Buffer Prenatal Stress in Mice.Research square · 2026Article
- Sexual aggression and prenatal stress lead to poor maternal care and aggressive behaviour in male Wistar rat offspring.IBRO neuroscience reports · 2026Article
- Germline and Embryonic Mechanisms in the Epigenetic Inheritance of Neurodevelopmental and Cognitive Traits in Mammals.Biomolecules · 2026Review
- The Future of Epigenetics: Emerging Technologies and Clinical Applications.ACS pharmacology & translational science · 2026Review
- Review
- Sex-dependent biobehavioural responses to transgenerational maternal stress: evidence of stress resilience and vulnerability in the F3 generation.Environmental epigenetics · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal stress exposure during pregnancy is known to affect offspring behavior, including learning and memory. We hypothesized that maternal stress-induced changes transmit this effect through maternal line mediated transgenerational epigenetic inheritance. To test our hypothesis, pregnant rats (F0) were undisturbed (Control, Ctrl)/exposed to social stress during gestational days (GD) 16-18 (PMS)/exposed to social stress and treated with oxytocin during GD-16 to 18 (PMS+OXT). Subsequently, F1 female offspring from Ctrl, PMS, and PMS+OXT were mated with Ctrl F1 males to examine maternal line mediated transgenerational impacts. Female animals (F1 and F2) were subjected to behavioral test and the levels of global H3K4me2/H3K4me3 methylation, methylation in the CRH promoter, expression of
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Registered trials
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