Evidence map›Paper›PMID 40018352›Full record

ArticleFrontiers in medicine2025

Peripheral-central correlation study of acupuncture for chronic tinnitus study protocol for a randomized controlled trial.

Da Jiang, Xiao-Han Huang, Ke Fang, Ming-Hui Zhao, Yang Li, Han-Tong Hu, Lian-Qiang Fang, Hong Gao, Jie Zhou

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06401993 (Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain"), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06401993 narecruitingnot on this map

Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain"

TypeinterventionalSponsorThe Third Affiliated hospital of Zhejiang Chinese Medical UniversityRan2024 to 2026Enrolled87ConditionsTinnitusArmsThe "dao qi tong luo" group, The acupuncture group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Da Jiang *Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Xiao-Han Huang *Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Ke FangDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Ming-Hui ZhaoDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Yang LiDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Han-Tong HuDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Lian-Qiang FangDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Hong GaoDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Jie ZhouDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: (1) Exploring the evaluation and correlation of peripheral central auditory function in patients with chronic tinnitus. (2) Evaluation of the cumulative effect of acupuncture on peripheral central auditory function in patients with chronic tinnitus. Method: Our research is structured as a regulated and randomized trial with assessor blinding. Seventy-two participants who qualify with chronic tinnitus will be allocated in a 1:1 ratio to either the acupuncture group or the sham acupuncture group. Additionally, we will recruit 15 healthy individuals as subjects for data collection to observe the correlation of peripheral-central auditory function under different physiological states. Result: Clinical result metrics encompass the Tinnitus Handicap Inventory (THI), ABR testing, and fNIRS data collection. Evaluations will be carried out at baseline, after 10 treatment sessions. Conclusion: This research are anticipated to improve our comprehension of the effectiveness and fundamental processes of acupuncture in addressing persistent tinnitus and deeply explain the mechanism of action of the acupuncture method on chronic tinnitus. Clinical trial registration: ClinicalTrials.gov, identifier NCT06401993.

Indexed as

ABRacupuncturechronic tinnitusfNIRSprotocolrandomized controlled trialtinnitus

Identifiers

PMID40018352
PMCPMC11865056

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.