Evidence map›Paper›PMID 40018339›Full record

ArticleJournal of family & community medicine

Akram's lifestyle: An effective remedy for the management of gastroesophageal reflux disease.

Sadia A Khan, Javeria Z Khan, Tayyab S Akhter, Hamama-Tul-Bushra Khaar, Talay Yar, Mohammad A Randhawa

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Article in Journal of family & community medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sadia A KhanDepartment of Family Medicine, Rawalpindi Medical University, RMU, Rawalpindi, Pakistan.
Javeria Z KhanCenter for Liver and Digestive Diseases, Holy Family Hospital, RMU, Rawalpindi, Pakistan.
Tayyab S AkhterCenter for Liver and Digestive Diseases, Holy Family Hospital, RMU, Rawalpindi, Pakistan.
Hamama-Tul-Bushra KhaarCenter for Liver and Digestive Diseases, Holy Family Hospital, RMU, Rawalpindi, Pakistan.
Talay YarDepartment of Physiology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mohammad A RandhawaDepartment of Pharmacology, RMU, Rawalpindi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe prevalence of gastroesophageal reflux disease (GERD) has generally increased worldwide. Irregular pattern of intake of meals are known to be the most prevalent cause of GERD. The intake of food on top of another meal may cause gastroesophageal reflux either by generating transient lower-esophageal sphincter relaxations (TLESRs) subsequent to distention of the upper part of the stomach or/and delayed gastric emptying due to inhibition of migrating motor complexes (MMCs) in the distal part of the stomach. Present study evaluated the effect of authors suggested regimen "Akram's lifestyle", taking meals twice-a-day with the liberty to consume only liquids in the intervening periods on the outcome of patients presenting with mild to moderate GERD. MATERIALS AND

methodsStudy included 60 patients with symptoms of GERD who agreed to follow "Akram's lifestyle", took two meals a day about 10-12 hours apart, consuming liquids in between meals for a period of two weeks. Typical GERD symptoms of heartburn, acid reflux, nausea, vomiting and dyspepsia as reported by the patients were scored on visual analog scale (VAS). Gastrointestinal and associated complaints were also evaluated by "Yes/No" response. Data obtained before and after two weeks of intervention was analyzed using SPSS version 28.0.

resultsFinal data after 2 weeks were available for 45 patients. There was a highly significant improvement in GERD symptoms (heartburn, reflux, nausea, vomiting, and dyspepsia) within 2 weeks of dietary intervention (

conclusionsAdherence to "Akram's lifestyle" for GERD for 2 weeks resulted in a significant improvement or complete relief of symptoms of patients with GERD. Reduced gastric acid secretion, TLESRs and enhanced gastric emptying could be the potential contributing factors in causing this improvement. Further investigations with larger samples are needed to confirm the findings.

Indexed as

Akram’s lifestylegastroesophageal reflux diseaseheartburnlifestyle modificationsmigrating motor complexes (MMC)proton pump inhibitorstransient lower esophageal sphincter relaxations

Identifiers

PMID40018339
PMCPMC11864353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.