Evidence map›Paper›PMID 40018332›Full record

ArticleJournal of family & community medicine

Frequency and characteristics of anemia in hypothyroid patients: A cross-sectional study.

Abdullah S Babaker, Reem M Al-Qahtani

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Article in Journal of family & community medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Abdullah S BabakerDepartment of Family Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Reem M Al-QahtaniDepartment of Family Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypothyroidism leads to a metabolic slowdown that affects all body systems and significantly impacts the hematopoietic system, resulting in anemia in 20%-60% of patients. This study aims to evaluate the prevalence of anemia in hypothyroid patients and describe the factors associated with anemia in those patients. MATERIALS AND

methodsWe reviewed the electronic health records (EHRs) of all the patients attending the Outpatient Department of King Abdulaziz University Hospital, Jeddah, Saudi Arabia, during January 1, 2018, to December 31, 2022. All patients aged 18-70 years who had received a diagnosis of hypothyroidism, ICD-10 code E03.9, and had undergone simultaneous blood tests for complete blood count and iron profile along with thyroid function tests were included in the study. Data on demographic characteristics, laboratory test results, and comorbidities was retrieved from EHRs. Anemia was defined according to WHO as Hb levels <12.0 g/dL in women and <13.0 g/dL in men. Data was analyzed using SPSS version 28.0. Categorical variables were presented as frequencies and percentages while continuous variables were described by mean and standard deviation. Multiple logistic regression was applied to determine the risk factors for hypothyroidism.

resultsStudy included a total of 413 patients with hypothyroidism; 40% of hypothyroid patients were found to be anemic and most had microcytic normochromic anemia. Logistic regression revealed that males had much lower risk of anemia compared to females (adjusted odds ratio [AOR] = 0.14; 95% confidence interval [CI]: 0.05-0.39), while obesity was associated with a higher risk of anemia (AOR = 1.67; 95% CI: 1.11-2.50).

conclusionA higher proportion of anemia was seen in patients with hypothyroidism, indicating a significant relationship between anemia, obesity, and gender. This highlights the importance of monitoring anemia in patients with hypothyroidism, especially in females and obese individuals.

Indexed as

Anemiafree thyroxinefree triiodothyroninehemoglobinhypothyroidismJeddahSaudi Arabiathyroid-stimulating hormone

Identifiers

PMID40018332
PMCPMC11864361

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