Evidence map›Paper›PMID 40018184›Full record

ArticleBMJ public health2024

Cost-effectiveness of screening for developmental dysplasia of the hip in Karachi, Pakistan using a universally applicable cost-effectiveness model.

Manon Pigeolet, Hesham Gaafar, Dana Naamani, Mansoor Ali Khan, Blake Christian Alkire, Muhammad Amin Chinoy, Daniel Scott Corlew, Eduardo N Novais

Abstract read
In one paragraph

Article in BMJ public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manon PigeoletFaculty of Medicine, Université Libre de Bruxelles, Bruxelles, Belgium.ORCID 0000-0003-0683-9520
Hesham GaafarPrecision Health Program, University of Chicago Biological Sciences Division, Chicago, Illinois, USA.
Dana NaamaniDepartment of Emergency Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Mansoor Ali KhanDepartment of Orthopedics, The Aga Khan University Hospital, Karachi, Pakistan.
Blake Christian AlkireThe Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA.
Muhammad Amin ChinoyDepartment of Orthopedics, Indus Hospital & Health Network, Karachi, Pakistan.
Daniel Scott CorlewThe Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-6101-0443
Eduardo N NovaisDepartment of Orthopaedic Surgery, Boston Children's Hospital, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Developmental dysplasia of the hip (DDH) is a congenital anomaly of the hip socket that can lead to lifelong disability and pain when left untreated. DDH is a good candidate for screening because of its high frequency in population, availability of treatment and the possibility of secondary prevention. Pakistan currently does not have any systematic or universal neonatal screening programme for DDH. Methods: The cost-effectiveness model in this study uses one decision tree for each screening scenario: (1) the status quo, (2) universal screening by clinical examination, (3) universal screening by clinical examination with targeted ultrasound (US) screening, (4) and universal screening by US. Loss of disability-adjusted life-years (DALYs) is used as outcome variable. Results: When left untreated DDH creates a loss of 3.4 DALYs per person. Clinical examination and targeted US averts most DALYs per dollar spent. Generalised US averts more DALYs overall but requires a greater financial investment per DALY averted. Conclusions: Universal US screening reaches more children and can be considered the more equitable approach but requires 10 times the financial investment clinical examination and targeted US requires. The decision which option is most appropriate for Karachi, Pakistan depends on resource availability, geography, infrastructure, treatment capacity, health system values and societal factors in Pakistan.

Indexed as

Community HealtheconomicsSecondary Prevention

Identifiers

PMID40018184
PMCPMC11812765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.