Evidence map›Paper›PMID 40017978›Full record

ArticleBMJ public health2025

Childhood socioeconomic position and healthy ageing: results from five harmonised cohort studies in the ATHLOS consortium.

Yu-Tzu Wu, Sam Gnanapragasam, Albert Sanchez-Niubo, Muhammad Zakir Hossin, Ilona Grünberger, Seppo Koskinen, Rachel Cooper, Matthew Prina

Abstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Tzu WuPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-0874-4448
Sam GnanapragasamDepartment of Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Albert Sanchez-NiuboDepartment of Social Psychology and Quantitative Psychology, University of Barcelona, Barcelona, Spain.
Muhammad Zakir HossinDepartment of Medicine Solna, Clinical Epidemiology Division, Karolinska Institute, Stockholm, Sweden.
Ilona GrünbergerDepartment of Public Health Sciences, Stockholm University, Stockholm, Sweden.
Seppo KoskinenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
Rachel CooperNIHR Newcastle Biomedical Research Centre, Northumberland Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
Matthew PrinaPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
China Health and Retirement Longitudinal StudyR01AG037031 · NIA · PEKING UNIVERSITY · PI STRAUSS, JOHN A, WANG, YAFENG · 2010 to 2024
$15.1M
Towards improving the measurement of health and disability trends, the compressioR01AG034479 · NIA · WORLD HEALTH ORGANIZATION · PI CHATTERJI, SOMNATH · 2010 to 2014
$5.3M
Health disparities and agingin societies in transitionR01AG023522 · NIA · UNIVERSITY COLLEGE LONDON · PI MARMOT, MICHAEL G · 2004 to 2008
$2.2M
Biomarkers in the China Health and Retirement Longitudinal StudyR21AG033675 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRIMMINS, EILEEN M, STRAUSS, JOHN A · 2009 to 2010
$369k
China Health and Retirement Longitudinal Study - PilotR21AG031372 · NIA · PEKING UNIVERSITY · PI ZHAO, YAOHUI · 2007 to 2008
$273k
NIA NIH HHS R01 AG017644NIA NIH HHS R01 AG023522NIA NIH HHS R01 AG034479NIA NIH HHS R01 AG037031NIA NIH HHS R21 AG031372NIA NIH HHS R21 AG033675Wellcome Trust
6 · The paper itself

Abstract

Introduction: Childhood socioeconomic position (SEP) has been identified as a key determinant of health. However, earlier literature is largely from high-income countries and provides limited evidence on the prolonging impacts of childhood disadvantage on healthy ageing across diverse settings and populations. The aim of this study is to investigate the associations between childhood SEP and healthy ageing across multiple countries and the mediation effects of adult SEP, individual education and wealth, on these associations. Methods: Using the harmonised dataset of five cohort studies in the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) project, this study was based on 57 956 people aged ≥50 years (women: 53.3%) living in China, Finland, UK, Poland, South Africa and Mexico. The associations between childhood SEP (parental education and occupation) and healthy ageing scores were examined using linear regression modelling. Causal mediation analysis was carried out to estimate the percentage of indirect effects via adult SEP (individual education and wealth). Results: Higher levels of childhood SEP were associated with higher healthy ageing scores by up to five points and similar patterns were observed across populations from different countries. The associations were mediated by adult SEP and the range of mediation effects was between 21% and 78%. Conclusions: This study found childhood SEP was associated with poor health in later life across high-income, middle-income and low-income countries. Addressing socioeconomic disadvantage, such as improving education attainment, may moderate the impacts of adversity in early life and support health and functioning in later life.

Indexed as

Age FactorsEpidemiologySociodemographic Factors

Identifiers

PMID40017978
PMCPMC11865732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.