Evidence map›Paper›PMID 40017955›Full record

ArticleBMJ public health2025

An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India: the YUVAAN cohort study protocol.

Demi Miriam, Rubina Mandlik, Vivek Patwardhan, Dipali Ladkat, Vaman Khadilkar, Neha Kajale, Chidvilas More, Ketan Gondhalekar, Jasmin Bhawra, Tarun Reddy Katapally and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in BMJ public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05603793 (YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05603793 active not recruitingnot on this map

YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition

TypeobservationalSponsorHirabai Cowasji Jehangir Medical Research InstituteRan2022 to 2050Enrolled1,304ConditionsArrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational DiabetesArmsKnowledge, Attitude & Practices
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Demi Miriam *Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0002-7331-5041
Rubina Mandlik *Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0002-4660-3013
Vivek PatwardhanHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0002-7985-9808
Dipali LadkatHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0003-3930-3669
Vaman KhadilkarHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0001-7719-1341
Neha KajaleHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0001-5129-481X
Chidvilas MoreHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0009-0001-0091-2160
Ketan GondhalekarHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0002-0266-8552
Jasmin BhawraSchool of Occupational and Public Health, Toronto Metropolitan University, Toronto, Ontario, Canada.ORCID 0000-0001-9926-8442
Tarun Reddy KatapallySchool of Health Studies, Western University, London, Ontario, Canada.ORCID 0000-0001-5765-1435
Anuradha Vaman KhadilkarHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharastra, India.ORCID 0000-0002-3399-3235

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Non-communicable diseases (NCDs) pose a significant health burden in India, with preventable risk factors contributing to their prevalence. In rural populations, inequalities may be reinforced by health risks passed down through generations. Taking a life course perspective, this multigenerational cohort study aims to investigate behavioural, socioecological, and socioeconomic determinants of growth and NCD risk, as well as healthcare access and utilisation among preadolescents and their parents. Methods and analysis: The study is being implemented by the Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) using a prospective, multigenerational cohort design to investigate NCD risk over 15 years. Data are being collected from 14 villages around Pune, Maharashtra, India. The target population is asymptomatic (ie, healthy) children aged 8-10 years and their parents. The study commenced on 13 September 2022. Participants (children and their parents) are being enrolled through household visits, and by arranging subsequent visits to the primary health facility of HCJMRI. After obtaining informed consent from participants (parents and their children), comprehensive data are being collected from both children and parents, including clinical, behavioural, healthcare access and utilisation, as well as socioeconomic determinants of health. Clinical assessments include anthropometric measurements, blood samples for a wide range of NCD indicators, bone health and muscle function. The long-term data analysis plan includes longitudinal modelling, time-series analyses, structural equation modelling, multilevel modelling and sex-based analyses to investigate growth trajectories and intergenerational patterns of health risks. As of November 2024, 1070 families from 14 villages have been enrolled (1264 preadolescents and 2140 parents). Given the double burden of malnutrition, with undernutrition and overweight/obesity coexisting among children and parents in India, the study findings will contribute to the development of focused interventions aimed at lowering NCDs, addressing the generational transmission of health risks, and improving health outcomes for rural communities. Ethics and dissemination: Ethics approval was obtained from the institutional ethics committee, Ethics Committee Jehangir Clinical Development Centre, No: JCDC/BHR/24/047. Trial registration number: NCT05603793.

Indexed as

AdolescentCommunity HealthPreventive MedicinePublic HealthSocial Medicine

Identifiers

PMID40017955
PMCPMC11812897

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.