ArticleJACS Au2025
DNA Nanotechnology in the Undergraduate Laboratory: Toehold-Less Strand Displacement in Switchback DNA.
Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- DNA Nanotechnology in the Undergraduate Laboratory: Isothermal Assembly and Quantification of DNA Nanostructures.JACS Au · 2026Article
- Dynamic DNA Nanomachines for Biosensing and Drug Delivery.Sensors (Basel, Switzerland) · 2026Review
- Left-Handed Helices in DNA Nanotechnology.JACS Au · 2026Review
- Kinetics and Activation Strategies in Toehold-Mediated and Toehold-Free DNA Strand Displacement.Biosensors · 2025Review
- Isothermal assembly of DNA nanostructures.Chemical communications (Cambridge, England) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Dynamic DNA nanostructures that reconfigure into different shapes are used in several applications in biosensing, drug delivery, and data storage. One of the ways to produce such structural transformations is by a process called strand displacement. This laboratory experiment demonstrates a strand displacement reaction in a two-stranded DNA nanostructure called switchback DNA by the addition of a third strand. In this process, the difference in the affinity between the component DNA strands is used to convert switchback DNA into conventional duplex DNA. Students are introduced to the concept through gel electrophoresis and quantitative analysis of DNA nanostructure reconfiguration. The experiment presented here is an example of DNA nanotechnology-based exercises in an undergraduate setting and is tailored for adaptation in a chemistry, biology, or biochemistry laboratory with minimal costs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.