Evidence map›Paper›PMID 40017677›Full record

ArticleNMC case report journal2025

A Case of Intracranial Mesenchymal Tumor, FET::CREB Fusion-positive, Diagnosed by Genomic Profiling with FoundationOne CDx.

Kousuke Sono, Toshiyuki Enomoto, Hiromasa Kobayashi, Koichiro Takemoto, Takashi Morishita, Mikiko Aoki, Makoto Hamasaki, Hiroshi Abe

Abstract readCase Reports
In one paragraph

Article in NMC case report journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Non-Meningothelial Mesenchymal Tumor of the Central Nervous System: Case Report and Literature Review.Neuropathology : official journal of the Japanese Society of Neuropathology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kousuke SonoDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Toshiyuki EnomotoDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Hiromasa KobayashiDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Koichiro TakemotoDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Takashi MorishitaDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Mikiko AokiDepartment of Pathology, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Makoto HamasakiDepartment of Pathology, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.
Hiroshi AbeDepartment of Neurosurgery, Faculty of Medicine Fukuoka University, Fukuoka, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracranial mesenchymal tumor FET::cyclic adenosine monophosphate response element-binding fusion-positive is a soft tissue tumor with an extremely rare intracranial occurrence. Histological diagnosis is sometimes difficult, requiring confirmation of characteristic fusion genes. The patient was a 45-year-old male who presented with a chief complaint of pain and an abnormal sensation in the right trigeminal nerve area, in whom a neoplastic lesion in Meckel's cave was noted. The preoperative diagnoses included meningioma and schwannoma. The tumor was extirpated as much as possible, and the tumor tissue showed a high proliferative potential with rhabdoid features, raising the suspicion of a rhabdoid meningioma. However, immunostaining was positive for desmin and cluster of differentiation 99, suggesting the possibility of angiomatoid fibrous histiocytoma. For diagnosis,

Indexed as

EWSR1-CREM fusionFoundationOne CDxintracranial mesenchymal tumor FET::CREB fusion-positive angiomatoid fibrous histiocytomaintracranial myxoid mesenchymal tumor

Identifiers

PMID40017677
PMCPMC11867763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.