Evidence map›Paper›PMID 40017643›Full record

ArticleRSC advances2025

Environmental innovation: polyaniline-cuttlebone nanocomposite as a potent antimicrobial agent and a synergistic barrier against doxorubicin-induced toxicity.

Esraa Salama, Fatma I Abo El-Ela, Walid Hamdy Hassan, Ahmed A Farghali, Abdullah A Eweis, Sarah H M Hafez, Rehab Mahmoud

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esraa SalamaChemistry Department, Faculty of Sciences, Beni-Suef University Beni-Suef 62511 Egypt Esraa6salama96@gmail.com.
Fatma I Abo El-ElaDepartment of Pharmacology, Faculty of Veterinary Medicine, Beni-Suef University Beni-Suef 62511 Egypt Fatma.aboel3la@vet.bsu.edu.eg.
Walid Hamdy HassanDepartment of Microbiology Mycology and Immunology, Faculty of Veterinary Medicine, Beni-Suef University 62511 Beni-Suef Egypt walidhamdyhassan@yahoo.com.
Ahmed A FarghaliDepartment of Materials Science and Nanotechnology, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef 62511 Egypt ahmedfarghali74@yahoo.com.
Abdullah A EweisDepartment of Botany and Microbiology, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt abdullah.ali@science.bsu.edu.eg.
Sarah H M HafezPhysics Department, Higher Technology Institute in New Heliopolis Cairo Egypt sarahafez789@gmail.com.
Rehab MahmoudChemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt rehabkhaled@science.bsu.edu.eg.ORCID https://orcid.org/0000-0003-2274-2016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work emphasizes the importance of utilizing cuttlebone waste as a sustainable solution for waste management and the development of antimicrobial materials by incorporating it as a supporting phase for polyaniline (PANI) to form a nanocomposite. The three prepared materials were fully characterized using various techniques, including FTIR, XRD, SEM, EDX for elemental analysis, Brunauer-Emmett-Teller (BET) surface area measurements, particle size distribution analysis, and zeta potential measurements. The study focuses on the development of novel molecules with potential antibacterial and antifungal activity against clinical pathogens responsible for infectious diseases. The antibacterial and antifungal activities of the polyaniline/cuttlebone (PANI/CB) composite were evaluated using methods such as minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and disk diffusion for bacterial samples, as well as MIC, minimum fungicidal concentration (MFC), antifungal percentage, and disk diffusion for fungal samples. Notably, the PANI/CB composite exhibited a distinct crystallite size and characteristic XRD pattern, along with a significant BET surface area, demonstrating strong antimicrobial properties. Cuttlebone not only serves as a bioactive agent but also acts as a sustainable support to enhance the properties of polyaniline, forming a nanocomposite with a low MIC range (8-66 μg mL

Identifiers

PMID40017643
PMCPMC11865944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.