Evidence map›Paper›PMID 40017526›Full record

ArticleEpilepsy & behavior reports2025

Ultrahigh-field imaging (7 Tesla) in DNET: Unmasking microstructural imaging characteristics - A case report.

Marta Calvo-Imirizaldu, Daniele Botta, Margitta Seeck, Jan Novy, Jose Federico Ojeda Esparza, Aikaterini Fitsiori, Corrado Santarosa, Kevin Battistini, Karl-Olof Lövblad, Felix T Kurz

Abstract read
In one paragraph

Article in Epilepsy & behavior reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Long-term follow-up of dysembryoplastic neuroepithelial tumour (DNET) with recurrent bleeds: a case report and review of literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marta Calvo-ImirizalduDepartment of Radiology, University Clinic of Navarra, Pamplona, Spain.
Daniele BottaDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Margitta SeeckDivision of Neurology, Geneva University Hospitals, Geneva, Switzerland.
Jan NovyDivision of Neurology, Lausanne University Hospitals, Lausanne, Switzerland.
Jose Federico Ojeda EsparzaDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Aikaterini FitsioriDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Corrado SantarosaDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Kevin BattistiniDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Karl-Olof LövbladDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.
Felix T KurzDivision of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Commercial ultrahigh-field 7 Tesla (T) MRI has been approved for clinical brain imaging, including applications in epilepsy and brain tumors. Increasing magnetic field strength offers significant advantages over lower-field MRI due to improved spatial resolution, signal-to-noise ratio, and contrast-to-noise ratio. These improvements provide better anatomical delineation and gray-white matter tissue-contrast differentiation. We present a case of a presumed dysembryoplastic neuroepithelial tumor (DNET) imaged at 7 T MRI of the second generation, which revealed an unprecedented level of detail of the complex and intricate tumor architecture. Insights of its different components correlate closely with its known histopathological features. These tumors are unique among low-grade neoplasms due to their distinct clinical presentation, imaging features, and histopathological architecture. DNETs are rare, typically occurring in young patients with refractory epilepsy, and are classified by their well-defined histological subtypes. We review the various MRI patterns of DNET, which have been shown to correlate with histological subtypes and the extent of the epileptogenic zone. Complete tumor resection is essential for long-term control and recurrence prevention, emphasizing the importance of precise preoperative visualization of the tumor and its surrounding tissue. In this case, 7 T images demonstrated superior lesion conspicuity and clearer boundaries, highlighting the advantages of ultrahigh-field MRI in defining the full extent of the lesion. Although 7 T MRI is not yet widely available, it has started to gain an important role in the management of epilepsy, particularly for cases requiring detailed structural analysis.

Indexed as

7T MRIDrug-resistant epilepsyDysembryoplastic neuroepithelial tumorFocal cortical dysplasiaSatellite lesion

Identifiers

PMID40017526
PMCPMC11867227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.