Evidence map›Paper›PMID 40017278›Full record

ArticlePsychiatry investigation2025

Differential Analysis of Heart Rate Variability in Repeated Continuous Performance Tests Among Healthy Young Men.

Chung-Chih Hsu, Tien-Yu Chen, Jia-Yi Li, Terry B J Kuo, Cheryl C H Yang

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Article in Psychiatry investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chung-Chih HsuInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tien-Yu ChenInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Jia-Yi LiSleep Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Terry B J KuoInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Cheryl C H YangInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Funding

Brain Research Center, National Yang Ming Chiao Tung University 112W32101National Science and Technology Council of Taiwan MOST 110-2629-B-A49A-501Tri-Service General Hospital TSGH-D-113147Tri-Service General Hospital TSGH-D-114144
6 · The paper itself

Abstract

objectiveExecutive function correlates with the parasympathetic nervous system (PNS) based on static heart rate variability (HRV) measurements. Our study advances this understanding by employing dynamic assessments of the PNS to explore and quantify its relationship with inhibitory control (IC).

methodsWe recruited 31 men aged 20-35 years. We monitored their electrocardiogram (ECG) signals during the administration of the Conners' Continuous Performance Test-II (CCPT-II) on a weekly basis over 2 weeks. HRV analysis was performed on ECG-derived RR intervals using 5-minute windows, each overlapping for the next 4 minutes to establish 1-minute intervals. For each time window, the HRV metrics extracted were: mean RR intervals, standard deviation of NN intervals (SDNN), low-frequency power with logarithm (lnLF), and high-frequency power with logarithm (lnHF). Each value was correlated with detectability and compared to the corresponding baseline value at t0.

resultsCompared with the baseline level, SDNN and lnLF showed marked decreases during CCPT-II. The mean values of HRV showed significant correlation with d', including mean SDNN (R=0.474, p=0.012), mean lnLF (R=0.390, p=0.045), and mean lnHF (R=0.400, p=0.032). In the 14th time window, the significant correlations included SDNN (R=0.578, p=0.002), lnLF (R=0.493, p=0.012), and lnHF (R=0.432, p=0.031). Significant correlation between d' and HRV parameters emerged only during the initial CCPT-II.

conclusionA significant correlation between PNS and IC was observed in the first session alone. The IC in the repeated CCPT-II needs to consider the broader neural network.

Indexed as

Executive functionHeart rate variabilityParasympathetic nervous system

Identifiers

PMID40017278
PMCPMC11878144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.