Evidence map›Paper›PMID 40017269›Full record

ArticleIntegrative zoology2026

Hypoxia Promotes Gluconeogenesis Through PGC-1α in the Liver of Lasiopodomys brandtii.

Mengke Li, Maolin Huang, Jun Wan, Yunfei Gao, Jiahui Song, Xiujuan Li, Qinghua Li, Han Cheng, Tian Shao, Zhenlong Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Integrative zoology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mengke LiSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Maolin HuangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Jun WanSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Yunfei GaoSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Jiahui SongSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Xiujuan LiSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Qinghua LiSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Han ChengSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Tian ShaoSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Zhenlong WangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China.

Funding

National Natural Science Foundation of China 32301302National Natural Science Foundation of China 32470501National Natural Science Foundation of China U2004152
6 · The paper itself

Abstract

Oxygen is a critical factor for the survival of most lifeforms, as inadequate availability disrupts internal metabolic balance. Hypoxia-induced disruptions in glucose metabolism can be fatal to many animals. However, there is currently limited research on the energy metabolism of species that inhabit environments with intermittently low oxygen levels. In this study, we investigated the gluconeogenic metabolic response patterns of adult Lasiopodomys brandtii (Brandt's vole) and Mus musculus (Kunming mice) under hypoxia (10% O

Indexed as

GluconeogenesisHypoxiaLiverPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaAnimalsAnimals, Outbred StrainsGene Expression RegulationMaleMiceOxygenOxygenPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphagluconeogenesishypoxiaLasiopodomys brandtiiliverPGC‐1α

Identifiers

PMID40017269
PMCPMC13574195

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.