Evidence map›Paper›PMID 40017243›Full record

ReviewCurrent cancer drug targets2026

Regulatory Effect of Non-Coding RNAs on Programmed Cell Death in Melanoma: Novel Therapeutic Crosstalk for Targeted Therapy.

Andarz Fazlollahpour-Naghibi, Seyed Reza Taha, Mahdieh Shariatzadeh, Danyal Daneshdoust, Kimia Bagheri, Tahereh Farkhondeh, Mohammad Samini, Mohammad Hossein Pourhanifeh, Saeed Samarghandian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cancer drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andarz Fazlollahpour-NaghibiFaculty of Medicine, Islamic Azad University, Sari Branch, Sari, Iran.
Seyed Reza TahaOncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mahdieh ShariatzadehOncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Danyal DaneshdoustSchool of Medicine, Babol University of Medical Sciences, Babol, Iran.
Kimia BagheriInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Tahereh FarkhondehDepartment of Toxicology and Pharmacology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran.
Mohammad SaminiDepartment of Neurosurgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Hossein PourhanifehStudent Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Saeed SamarghandianDepartment of Medical Physiology, School of Medicine, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma, one of the most fatal and aggressive types of skin cancer, is a malignant tumor created from pigment-producing cells called melanocytes. The morbidity and incidence rate of melanoma are increasing around the world. Considering all developments in diagnostic and therapeutic approaches, early diagnosis and more effective targeted therapies are still urgent for melanoma. Non-coding RNAs (ncRNAs), including microRNAs and long non-coding RNAs, are key role players in fundamental cellular processes and have various biological properties. It has been demonstrated that the dysregulation of these biomarkers contributes to melanoma pathogenesis. Furthermore, programmed cell death (PCD), as an important cellular event, has been shown to play a role in the initiation and progression of cutaneous melanoma. Recent investigations have reported that the interplay between ncRNAs and PCD can be considered a novel choice for targeted therapy in melanoma. Thus, this review discusses PCD-related ncRNAs in melanoma, focusing on underlying pathways.

Indexed as

ApoptosisMelanomaRNA, UntranslatedSkin NeoplasmsAnimalsGene Expression Regulation, NeoplasticHumansMicroRNAsMolecular Targeted TherapyMicroRNAsRNA, Untranslatedapoptosisautophagyferroptosislong non-coding RNAMelanomamicroRNAnon-coding RNApyroptosis

Identifiers

PMID40017243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.