SynthesisBrain and behavior2025
Prevalence and risk of cognitive impairment among patients with asthma: A systematic review and meta-analysis.
Synthesis in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and risk of cognitive impairment among patients with asthma: A systematic review and meta-analysis.Brain and behavior · 2025Pooled it
- Article
- Prevalence and risk factors of cognitive impairment in patients with coronary heart disease: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundAsthma, a prevalent chronic respiratory condition, is hypothesized to influence cognitive health; however, the precise nature of this association remains unclear. This systematic review and meta-analysis aimed to elucidate the prevalence and risk of cognitive impairment in individuals with asthma.
methodsA comprehensive literature search was performed in databases such as PubMed, EMBASE, and Web of Science, spanning publications up to December 25, 2023. This search aimed to identify studies that assessed cognitive impairment in patients with asthma. We used the random effects model in the R v4.3 software for the meta-analysis to evaluate the prevalence and risk of cognitive decline, including dementia and Alzheimer's disease, among asthma patients. To ensure robustness and validity, the quality of the studies was assessed using Newcastle-Ottawa scale.
resultsTwelve studies met the inclusion criteria, of these 10 were eligible for meta-analysis. The pooled prevalence of cognitive impairment in patients with asthma was 16.3%. The analysis also revealed an increased hazard ratio of 1.47 (95% confidence interval [1.09; 1.84]) for cognitive impairment in patients with asthma compared to the control group (individuals without asthma). Significant heterogeneity and publication bias were observed across the studies. The results underscored the substantial correlation between asthma and heightened risks of cognitive decline, dementia, and Alzheimer's disease.
conclusionThis review found a notable association between asthma and an increased risk of cognitive decline, including dementia and Alzheimer's disease. These findings highlight the importance of integrating cognitive health assessments into asthma care. Further research is required to understand this relationship and develop effective treatments. Emphasizing a holistic approach to asthma management, these findings highlight the need to consider both respiratory and cognitive health for comprehensive patient care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.