Evidence map›Paper›PMID 40017039›Full record

ArticleHuman brain mapping2025

Longitudinal Changes of Quantitative Brain Tissue Properties Induced by Balance Training.

Norman Aye, Nico Lehmann, Jörn Kaufmann, Hans-Jochen Heinze, Emrah Düzel, Gabriel Ziegler, Marco Taubert

Abstract read
In one paragraph

Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Norman AyeFaculty of Human Sciences, Institute III, Department of Sport Science, Otto von Guericke University, Magdeburg, Germany.ORCID 0000-0002-6913-3229
Nico LehmannFaculty of Human Sciences, Institute III, Department of Sport Science, Otto von Guericke University, Magdeburg, Germany.ORCID 0000-0002-3146-5084
Jörn KaufmannDepartment of Neurology, Otto von Guericke University, Magdeburg, Germany.ORCID 0000-0002-8513-7043
Hans-Jochen HeinzeDepartment of Neurology, Otto von Guericke University, Magdeburg, Germany.
Emrah DüzelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.ORCID 0000-0002-0139-5388
Gabriel ZieglerGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.ORCID 0000-0001-6589-6416
Marco TaubertFaculty of Human Sciences, Institute III, Department of Sport Science, Otto von Guericke University, Magdeburg, Germany.ORCID 0009-0001-8483-5894

Funding

Otto von Guericke University Magdeburg 2039236003
6 · The paper itself

Abstract

The human brain can show remarkable experience-induced plasticity under conditions such as aging and pathology. However, the mapping of changes provided by many imaging approaches often lacks specificity with respect to biological tissue properties, which is relevant for treatment optimization and the evaluation of health-promoting lifestyle factors. Training-induced structural changes in cortical and subcortical gray matter likely reflect a mixture of various microstructural processes. In order to non-invasively map these different microstructural contributions, we used quantitative magnetic resonance imaging (qMRI) to measure clinically-relevant brain tissue property changes (such as iron, myelin, and water) in response to 4 weeks of motor balance training in 26 healthy young adults. Training resulted in a regionally-specific decrease in myelin-related magnetization transfer saturation (MT

Indexed as

BrainNeuronal PlasticityPostural BalanceAdultBrain MappingFemaleGray MatterHumansIronLongitudinal StudiesMagnetic Resonance ImagingMaleMyelin SheathYoung AdultIronbrain microstructuremotor learningMPMMRIneuroplasticity

Identifiers

PMID40017039
PMCPMC11868441

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.