Evidence map›Paper›PMID 40017036›Full record

ArticlePlant communications2025

EasyOmics: A graphical interface for population-scale omics data association, integration, and visualization.

Yu Han, Qiao Du, Yifei Dai, Shaobo Gu, Mengyu Lei, Wei Liu, Wenjia Zhang, Mingjia Zhu, Landi Feng, Huan Si and 2 more

Abstract read
In one paragraph

Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yu HanTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China; Key Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu 610065, China; Department of Plant Physiology, Umeå Plant Science Center and Integrated Science Lab, Umeå University, Umeå, Sweden.
Qiao DuTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China.
Yifei DaiBiostatistics Department, School of Public Health, University of Michigan, Ann Arbor, MI 48105, USA.
Shaobo GuKey Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu 610065, China.
Mengyu LeiTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China.
Wei LiuKey Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu 610065, China.
Wenjia ZhangTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China.
Mingjia ZhuState Key Laboratory of Herbage Innovation and Grassland Agro-ecosystem, College of Ecology, Lanzhou University, Lanzhou 730000, China.
Landi FengKey Laboratory for Bio-Resource and Eco-Environment of Ministry of Education & Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station, College of Life Science, Sichuan University, Chengdu 610065, China.
Huan SiTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China.
Jianquan LiuState Key Laboratory of Herbage Innovation and Grassland Agro-ecosystem, College of Ecology, Lanzhou University, Lanzhou 730000, China. Electronic address: liujq@nwipb.ac.cn.
Yanjun ZanTobacco Research Institute, Chinese Academy of Agricultural Sciences, Qingdao 266000, China; Department of Plant Physiology, Umeå Plant Science Center and Integrated Science Lab, Umeå University, Umeå, Sweden. Electronic address: zanyanjun@caas.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

The rapid growth of population-scale whole-genome resequencing, RNA sequencing, bisulfite sequencing, and metabolomic and proteomic profiling has led quantitative genetics into the era of big omics data. Association analyses of omics data, such as genome-, transcriptome-, proteome-, and methylome-wide association studies, along with integrative analyses of multiple omics datasets, require various bioinformatics tools, which rely on advanced programming skills and command-line interfaces and thus pose challenges for wet-lab biologists. Here, we present EasyOmics, a stand-alone R Shiny application with a user-friendly interface that enables wet-lab biologists to perform population-scale omics data association, integration, and visualization. The toolkit incorporates multiple functions designed to meet the increasing demand for population-scale omics data analyses, including data quality control, heritability estimation, genome-wide association analysis, conditional association analysis, omics quantitative trait locus mapping, omics-wide association analysis, omics data integration, and visualization. A wide range of publication-quality graphs can be prepared in EasyOmics by pointing and clicking. EasyOmics is a platform-independent software that can be run under all operating systems, with a docker container for quick installation. It is freely available to non-commercial users at Docker Hub https://hub.docker.com/r/yuhan2000/easyomics.

Indexed as

Computational BiologyGenomicsSoftwareComputer GraphicsGenome-Wide Association StudyMetabolomicsProteomicsQuantitative Trait LociUser-Computer Interfaceassociation analysisbioinformaticsdata visualizationomics data

Identifiers

PMID40017036
PMCPMC12143152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.