Evidence map›Paper›PMID 40016948›Full record

ReviewImmunological reviews2025

Chronic Inflammation in Asthma: Looking Beyond the Th2 Cell.

Simone E M Olsthoorn, Anneloes van Krimpen, Rudi W Hendriks, Ralph Stadhouders

Abstract readReview
In one paragraph

Review in Immunological reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Phenotyping treatment-naive uncontrolled asthma in adults: A primary care framework.The journal of allergy and clinical immunology. Global · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Ameliorating Effects ofAntioxidants (Basel, Switzerland) · 2026
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simone E M OlsthoornDepartment of Pulmonary Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Anneloes van KrimpenDepartment of Pulmonary Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Rudi W HendriksDepartment of Pulmonary Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Ralph StadhoudersDepartment of Pulmonary Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0002-1060-5607

Funding

European Molecular Biology Organization YIP5868Lung Foundation Netherlands 3.2.12.067Lung Foundation Netherlands 3.2.12.087Lung Foundation Netherlands 4.1.18.226Lung Foundation Netherlands 4.2.19.041JONederlandse Organisatie voor Wetenschappelijk Onderzoek 09120232310020Nederlandse Organisatie voor Wetenschappelijk Onderzoek 09150172010068Stichting Astma Bestrijding 2022/007
6 · The paper itself

Abstract

Asthma is a common chronic inflammatory disease of the airways. A substantial number of patients present with severe and therapy-resistant asthma, for which the underlying biological mechanisms remain poorly understood. In most asthma patients, airway inflammation is characterized by chronic activation of type 2 immunity. CD4

Indexed as

AsthmaInflammationTh2 CellsAnimalsChronic DiseaseCytokinesHumansImmunity, InnateCytokinesasthmacytokinesILC2Tc2 cellTh2 celltype 2 inflammation

Identifiers

PMID40016948
PMCPMC11868696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.