ArticleNeurorehabilitation and neural repair2025
Using a Functional Upper Limb Motor Task to Predict Cognitive and Functional Decline in Mild Cognitive Impairment and Alzheimer's Disease.
Article in Neurorehabilitation and neural repair, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- White matter microstructure and motor function in amnestic mild cognitive impairment and Alzheimer's dementia.Neuroimage. Reports · 2026Article
- Article
- Predicting the onset of dementia with longitudinal performance-based measures of physical function.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundPredicting the rate of cognitive and functional decline over the course of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) is vital for advancing clinical care and research initiatives.
objectivesThe current study examined if a functional upper limb motor task could predict 1-year change in cognition (Mini Mental Status Examination [MMSE]) and daily function (Quick Dementia Rating System [QDRS]) from a sample of 61 cognitively intact, 35 MCI, and 32 AD subjects.
resultsAnalyses adjusted for age, sex, and education showed that performance speed and variability on the motor task significantly predicted change in performance on the MMSE and QDRS over 1 year, and that these effects were small to medium in size (η
conclusionThese results suggest the potential of a simple motor task to estimate disease progression in MCI and AD, which could be used to provide additional clinical resources for and enrich clinical trials with those most likely to decline.
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