Evidence map›Paper›PMID 40016853›Full record

SynthesisJournal of ovarian research2025

Prognostic significance of systemic immune inflammation index for ovarian cancer: An updated systematic review and meta-analysis.

Boliang Chu, Yingying Chen, Jiewei Pan

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Boliang ChuDepartment of Gynecology, Huzhou Maternity & Child Health Care Hospital, No. 2, East Street, Wuxing District, Huzhou, Zhejiang Province, 313000, China.
Yingying ChenDepartment of Gynecology, Huzhou Maternity & Child Health Care Hospital, No. 2, East Street, Wuxing District, Huzhou, Zhejiang Province, 313000, China.
Jiewei PanDepartment of Gynecology, Huzhou Maternity & Child Health Care Hospital, No. 2, East Street, Wuxing District, Huzhou, Zhejiang Province, 313000, China. jieweipan2023@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSeveral inflammatory indices have been used to assess the prognosis of ovarian cancer, with variable results. This review assessed whether the systemic immune inflammation index (SII) can predict outcomes in patients with ovarian cancer.

methodsEmbase, PubMed, CENTRAL, Web of Science, and Scopus databases were searched by the two reviewers from inception to 15th October 2024 for studies assessing the relationship between SII and overall survival (OS) or disease-free survival (DFS).

resultsTen studies with eleven cohorts were included. Pooled analysis showed that higher SII was a significant predictor of poor OS (HR: 2.35 95% CI: 1.56, 3.55 I

conclusionsSII can be a potential predictor of OS and DFS after ovarian cancer. Further studies are required to improve the evidence.

Indexed as

InflammationOvarian NeoplasmsFemaleHumansPrognosisInflammationMalignancyMarkerOvaryRisk factorSurvival

Identifiers

PMID40016853
PMCPMC11869409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.