Evidence map›Paper›PMID 40016847›Full record

ArticleMolecular brain2025

Extinction of contextual fear memory is facilitated in TRPM2 knockout mice.

Seung Yeon Ko, Do Gyeong Kim, Huiju Lee, Sung Jun Jung, Hyeon Son

Erratum issuedAbstract read
In one paragraph

Article in Molecular brain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Seung Yeon Ko *Hanyang Biomedical Research Institute, Hanyang University, Seongdong-gu, Seoul, 04763, Korea.
Do Gyeong Kim *Graduate School of Biomedical Science and Engineering, Hanyang University, Seongdong-gu, Seoul, 04763, Korea.
Huiju Lee *Graduate School of Biomedical Science and Engineering, Hanyang University, Seongdong-gu, Seoul, 04763, Korea.
Sung Jun JungDepartment of Physiology, College of Medicine, Hanyang University, Seongdong-gu, Seoul, 04763, Korea. eurijj@hanyang.ac.kr.
Hyeon SonHanyang Biomedical Research Institute, Hanyang University, Seongdong-gu, Seoul, 04763, Korea. hyeonson@hanyang.ac.kr.

Funding

the National Research Foundation of Korea 2021R1A2C2011021the National Research Foundation of Korea RS202300240739the research fund of Hanyang University HY-2020
6 · The paper itself

Abstract

Transient receptor potential melastatin type 2 (TRPM2) is a nonselective cation channel involved in synaptic plasticity. We investigated its role in contextual fear conditioning and extinction of conditioned fear using Trpm2-deficient (Trpm2

Indexed as

Extinction, PsychologicalFearMemoryTRPM Cation ChannelsAnimalsBasic Helix-Loop-Helix ProteinsDentate GyrusEarly Growth Response Protein 1Freezing Reaction, CatalepticHippocampusMaleMiceMice, Inbred C57BLMice, KnockoutBasic Helix-Loop-Helix ProteinsEarly Growth Response Protein 1Npas4 protein, mouseTRPM2 protein, mouseTRPM Cation ChannelsExtinctionFear memoryTransient receptor potential melastatin type 2 (TRPM2)

Identifiers

PMID40016847
PMCPMC11869647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.