ArticleBMC sports science, medicine & rehabilitation2025
Effectiveness of high-intensity interval training in rehabilitation nursing for mild-to-moderate stable COPD patients: a randomized controlled clinical trial.
Article in BMC sports science, medicine & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- The SINFONIA Study: A Randomised Controlled Trial to Determine Feasibility and Effectiveness of Online Group Singing for People With COPD or ILD and Breathlessness.Respirology (Carlton, Vic.) · 2026Trial
- Response to Comment on "Periodizing Exercise Medicine Prescription for Patients with Cancer: A Narrative Opinion".Sports medicine (Auckland, N.Z.) · 2026Article
- Frailty and COPD: a bidirectional relationship in the context of systemic and accelerated ageing.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Exercise-induced gut microbiota metabolites and the gut-lung axis: implications for chronic obstructive pulmonary disease.Journal of thoracic disease · 2026Review
- High-intensity interval training alleviates COPD-induced gastrocnemius muscle dysfunction via the BRD4/PGC-1α axis through restoring mitochondrial function and oxidative fiber composition.Journal of muscle research and cell motility · 2026Article
- Exercise and Epigenetic Regulation in COPD: Current Evidence and Potential Mechanistic Pathways.International journal of molecular sciences · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe current study was conducted to explore the clinical impact of high-intensity interval training (HIIT) in rehabilitation nursing on improving cardiopulmonary function and exercise capacity in COPD patients.
methodsA total of thirty-one COPD patients underwent HIIT, while an equal number underwent moderate-intensity continuous training (MICT) were included in this randomized controlled clinical study. The randomization method used was stratified block randomization, stratified by center. During the 6 months follow-up period, the clinical data, including cardiopulmonary exercise testing (CPET) results, cardiopulmonary function index, quality of life, and follow-up outcomes, were collected before and after the interventions. The therapeutic effects of the two groups were compared.
resultsAfter the intervention, the HIIT group exhibited significantly higher peak power, exercise test duration, anaerobic threshold, peak oxygen uptake, peak ventilation, FEV1/FVC ratio, FEV1% of expected value, LVEF (%), and SF-36 scores compared to the MICT group (P < 0.05). Moreover, LVEDD was significantly lower in the HIIT group compared to the MICT group (P < 0.05). At the 6-month follow-up, the incidence of COPD acute exacerbation in the HIIT group was significantly lower than in the MICT group (P < 0.05).
conclusionImplementation of HIIT in rehabilitation nursing effectively improved cardiopulmonary function and exercise capacity in COPD patients during clinical treatment, highlighting its promising application potential.
trial registrationThis study was previously registered at Chinese Clinical Trial Registry (Date 11/05/2022 Number ChiCTR2200059764).
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