Evidence map›Paper›PMID 40016819›Full record

ArticleJournal of translational medicine2025

Association among measurements obtained using portable ultrasonography with sex, body mass index, and age in a large sample of adult population.

Giuseppe Annunziata, Ludovica Verde, Alessia Rosaria Anna Grillo, Tiziana Stallone, Annamaria Colao, Giovanna Muscogiuri, Luigi Barrea

Abstract read
In one paragraph

Article in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe Annunziata *Facoltà di Scienze Umane, della Formazione e dello Sport, Università Telematica Pegaso, Via Porzio, Centro Direzionale, Isola F2, Naples, 80143, Italy.ORCID 0000-0002-1922-662X
Ludovica Verde *Department of Public Health, University of Naples Federico II, Via Sergio Pansini 5, Naples, 80131, Italy.ORCID 0000-0002-4583-8283
Alessia Rosaria Anna GrilloCORPO LIBERO S.S.D.R.L. Società Sportiva Dilettantistica, Via Ca' Silvestri 16, Padua, 35136, Italy.
Tiziana StalloneDepartmental Faculty of Medicine, UniCamillus-Saint Camillus International University of Health Sciences, Via Di Sant'Alessandro 8, Rome, 00131, Italy.
Annamaria ColaoUnità di Endocrinologia, Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Via Sergio Pansini 5, Naples, 80131, Italy.ORCID 0000-0003-4049-2559
Giovanna Muscogiuri *Unità di Endocrinologia, Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Via Sergio Pansini 5, Naples, 80131, Italy.ORCID 0000-0002-8809-4931
Luigi Barrea *Dipartimento di Psicologia e Scienze della Salute, Università Telematica Pegaso, Centro Direzionale Isola F2, Via Porzio, Naples, 80143, Italy. luigi.barrea@unipegaso.it.ORCID 0000-0001-9054-456X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe assessment of the site-specific distribution of subcutaneous tissues (ST) represents an important addition to the body composition (BC) estimation. In this context, ultrasound stands out as a valuable method. However, the absence of reference values complicates both the interpretation of the obtained parameters and the monitoring of their changes during nutritional interventions or training programs.

methodsA total of 6,270 ultrasound images obtained with a technique using a non-diagnostic B-mode 2.5 MHz ultrasound probe (BodyMetrixTM, IntelaMetrix, Inc., Livermore, CA, USA) were obtained from adult men and women and analysed by grouping them according to sex, body mass index (BMI), and age. The thicknesses of total (tSAT), superficial (sSAT), and deep (dSAT) subcutaneous adipose tissue and muscle (MT), their ratios (sSAT/dSAT and MT/SAT), and muscle echogenicity (EG) were measured at the abdomen, thigh, chest, triceps, and hip sites.

resultsWomen exhibited greater tSAT, sSAT, dSAT, and EG (p < 0.001) and lower MT (p < 0.001), sSAT/dSAT (p = 0.008 for the abdomen and p < 0.001 for the thigh), and MT/SAT (p < 0.001) compared to men at both the abdomen and thigh sites. SAT-related parameters showed significant correlations with BMI, with thicknesses correlating positively and ratios negatively (p < 0.001). Muscle-related parameters correlated significantly with age, with MT and EG showing positive correlations and MT/SAT showing negative correlations (p < 0.001) in both sexes. Among SAT parameters, dSAT showed the strongest association with BMI in both men and women.

conclusionsThis study is the first to report the mean values of SAT-related quantitative and qualitative measurements (thickness and EG) in various body sites assessed through ultrasound and their associations with sex, BMI, and age in a large cohort. These findings could prove valuable in clinical practice for precise monitoring of nutritional and/or training interventions, as well as for a more comprehensive evaluation of nutritional status.

Indexed as

Body Mass IndexSex CharacteristicsAdultAgedAge FactorsBody CompositionFemaleHumansMaleMiddle AgedSex FactorsUltrasonographyYoung AdultEchogenicityMuscleObesitySubcutaneous adipose tissueTissue qualityUltrasound

Identifiers

PMID40016819
PMCPMC11869708

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.