Evidence map›Paper›PMID 40016786›Full record

ReviewEuropean journal of medical research2025

Multiple roles of circular RNAs in prostate cancer: from the biological basis to potential clinical applications.

Xianping Zheng, Ling Song, Ce Cao, Shoutian Sun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xianping Zheng *Intensive Care Unit, Zibo Central Hospital, Zibo, 255024, China.
Ling Song *Department of Emergency, Zibo Central Hospital, No. 54 Gongqingtuan Road, Zhangdian District, Zibo, 255024, China.
Ce CaoDepartment of Gastrointestinal Surgery, Zibo Central Hospital, Zibo, 255024, China.
Shoutian SunDepartment of Emergency, Zibo Central Hospital, No. 54 Gongqingtuan Road, Zhangdian District, Zibo, 255024, China. sunstzb2011@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is an important health concern affecting men. Circular RNAs (circRNAs) play an important molecular biological role in regulating gene expression due to their unique structure. Studies have revealed the involvement of circRNAs in many human diseases. In prostate cancer, circRNAs can act as oncogenes or tumour suppressor genes and affect cancer cell proliferation, invasion, resistance to chemotherapy and, consequently, disease progression. Accordingly, prostate cancer-related circRNAs are expected to serve as new targets in early clinical diagnosis and targeted therapy, but the various roles of circRNAs in prostate cancer have not been fully elucidated. This article reviews the molecular pathological roles of circRNA in prostate cancer and explores its prospects as a translational medicine in clinical treatment and prognostic evaluation.

Indexed as

Prostatic NeoplasmsRNA, CircularBiomarkers, TumorGene Expression Regulation, NeoplasticHumansMalePrognosisBiomarkers, TumorRNA, CircularChemotherapy resistanceCircular RNAsProstate cancerRadiotherapy resistance

Identifiers

PMID40016786
PMCPMC11866600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.