Evidence map›Paper›PMID 40016702›Full record

ArticleBMC endocrine disorders2025

Abdominal volume index is associated with higher oxidized LDL, high blood pressure and lower HDL among obese adults.

Mansuor Ahmed Alanazi, Khaled Alshehri, Faisal H Alerwy, Tariq Alrasheed, Hassan Fareed M Lahza, Nisreen Khalid Aref Albezrah, Yazeed Ibrahim Alghabban, Mahfoudh Almusali Mohammed Abdulghani

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Article in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Mansuor Ahmed AlanaziDepartment of Family Medicine, University of Tabuk, Tabuk, Saudi Arabia. mansuorahmedalanazi@gmail.com.
Khaled AlshehriDepartment of Internal Medicine, University of Tabuk, Tabuk, 47713, Saudi Arabia.
Faisal H AlerwyInternal Medicine and Adult Nephrology, Internal Medicine department, Faculty of Medicine, Universty of Tabuk, Tabuk, Saudi Arabia.
Tariq AlrasheedAmerican Board Certified in Internal Medicine and Endocrinology, Diabetes & Metabolism, Department of Internal Medicine, University of Tabuk, Tabuk, Saudi Arabia.
Hassan Fareed M LahzaDepartment of Information Systems, College of Computers and Information Systems, Umm Al-Qura University, Post-code 21955, Makkah, Saudi Arabia.
Nisreen Khalid Aref AlbezrahDepartment of Obstetric & Gynecology, College of Medicine, Taif University, Saudi Arabia, P.O.Box 11099, Taif, Taif, 21944, Saudi Arabia.
Yazeed Ibrahim AlghabbanDepartment of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia.
Mahfoudh Almusali Mohammed AbdulghaniPharmacy Department, Faculty of Medicine, and Health Sciences, University Science and Technology, Aden, Yemen. mahfoudhalmusalimohammedabdulg@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCentral obesity is a well-known risk factor of numerous disease. Numerous indicators are developed for central obesity measurement, among them, abdominal volume index (AVI), reflecting total volume of the abdomen, precisely estimates the visceral fat volume. As a relatively new health measure and potent prognostic marker of metabolic disturbances, no study is available to investigate its role in cardio-metabolic health and oxidized LDL among obese young adults. In the current study we aimed to evaluate the association between abdominal volume index (AVI) with cardio-metabolic profile including serum lipids, glycemic markers of serum glucose, hemoglobin (Hb) A

methodsTwo hundred twenty young adults aged 18 to 25 years old with overweight or obesity were enrolled in the current study. Anthropometric measurements were done and AVI were calculated. Biochemical variables including serum total cholesterol (TC), low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), triglyceride (TG), glycemic markers, including fasting serum glucose (FBS), insulin, hemoglobin (Hb) A

resultsParticipants in the third tertiles of AVI had higher body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) (p < 0.001 for all). Among biochemical variables, oxidized LDL, TG and HDL demonstrated significant associations across AVI tertiles in the first and second models, with higher oxidized LDL and TG and lower HDL levels observed in higher AVI tertiles (p < 0.05). Moreover, those at the highest AVI tertiles showed significantly higher odds ratios for elevated cardio-metabolic index and systolic and diastolic blood pressures compared to the first tertiles (p < 0.05).

conclusionsIn the current study, we comprehensively investigated the association between AVI with cardio-metabolic health in young obese adults and accordingly, AVI was unfavorably associated with metabolic health among obese adults. Further studies are needed to elaborate the underlying mechanisms. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Cholesterol, HDLHypertensionLipoproteins, LDLObesityAdolescentAdultBiomarkersBlood PressureBody Mass IndexCross-Sectional StudiesFemaleFollow-Up StudiesHumansMalePrognosisWaist CircumferenceBiomarkersCholesterol, HDLLipoproteins, LDLoxidized low density lipoproteinAbdominal volume indexAVICardio-metabolic healthCentral obesityObesityOxidized LDL

Identifiers

PMID40016702
PMCPMC11869561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.