Evidence map›Paper›PMID 40016655›Full record

ArticleBMC anesthesiology2025

Minimising the usage of desflurane only by education and removal of the vaporisers - a before-and-after-trial.

Ferdinand Lehmann, Johannes Mader, Christian Koch, Melanie Markmann, Dominik Leicht, Michael Sander

Abstract read
In one paragraph

Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ferdinand LehmannDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany. ferdinand.lehmann@chiru.med.uni-giessen.de.
Johannes MaderDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany.
Christian KochDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany.
Melanie MarkmannDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany.
Dominik LeichtDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany.
Michael SanderDepartment of Anaesthesiology, Operative Intensive Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig University Giessen, Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBy exceeding planetary environmental boundaries, multiple global crises have become imminent in the 21st century. The healthcare system is a contributor to the climate crisis, accounting for approximately 5% of greenhouse gas emissions in Western countries. In anaesthetic clinics, desflurane, a highly potent greenhouse gas and volatile anaesthetic with no compelling indications, accounts for up to two thirds of total emissions. Its use can be drastically reduced using simple measures. In the present study, we investigated whether a relevant and timely reduction in use could be achieved by dismounting desflurane vaporisers and providing information to the team without restricting its use.

methodsThe study was conducted in a German university hospital with approximately 1250 beds, over a 12-month period between 2021 and 2022, with a comparison to the corresponding periods of the previous years up to 2017. The interventions were, first, the removal of desflurane vaporisers, and second, staff education on the climate impact of volatile anaesthetics. The primary outcome variable was the reduction of hypnotic-related emissions in CO

resultsProspective data collection and interventions were conducted from 28 March 2021 to 27 March 2022. The amount of CO

conclusionsRemoval of desflurane vaporisers and staff training can quickly and significantly reduce the emissions of an anaesthesia department in a large German teaching hospital. This may also reduce the costs.

trial registrationThe trial was registered with the German Clinical Trials Register, identifier DRKS00024973 on 12/04/2021.

Indexed as

Anesthetics, InhalationDesfluraneNebulizers and VaporizersGermanyGreenhouse GasesHospitals, UniversityHumansProspective StudiesAnesthetics, InhalationDesfluraneGreenhouse GasesAwareness of environmental protectionCarbon footprintDesfluraneGeneral anaesthesiaSustainability

Identifiers

PMID40016655
PMCPMC11866676

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.