ArticleBMC immunology2025
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension.
Article in BMC immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Age-Related Patterns of Myocardial Recovery After Primary PCI for Acute Myocardial Infarction: A Prospective 12-Month Study.Biomedicines · 2026Article
- Research status and hotspots of the systemic immune-inflammation index: A bibliometric analysis.Medicine · 2026Article
- Article
- Systemic immune-inflammation index: a novel tool for hypertension management in primary care.BMC primary care · 2026Article
- Article
- The correlation between the systemic inflammation response index and 6-month readmission risk in patients with hypertensive heart disease-related heart failure and its predictive model.Frontiers in medicine · 2026Article
- Association between the systemic immune-inflammation index and mortality risk in myocardial infarction patients: a retrospective cohort study.European journal of medical research · 2025Article
- Association of product of platelet and neutrophil count with monoclonal gammopathy of undetermined significance: a cross-sectional analysis of the NHANES.Blood research · 2025Article
- Effects of bisoprolol combined with torasemide on cardiac electrophysiology in patients with acute myocardial infarction and heart failure.Frontiers in physiology · 2025Article
- Physiological-immune resilience risk assessment model for predicting adverse cardiac outcomes in patients with acute myocardial infarction.Frontiers in cardiovascular medicine · 2025Article
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5 authors.
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Abstract
backgroundA new indicator of immunological and inflammatory condition, the Systemic Immunoinflammatory Index (SII), has been linked to a bad prognosis in a number of disorders.
methodsTwo thousand three hundred seventeen ICU patients were admitted with hypertension and acute myocardial infarction (AMI). Patients were grouped according to their baseline SII tertile number into Q1, Q2, and Q3 groups. The main outcomes were death from all causes at 30 days, 365 days, cardiogenic shock, and congestive heart failure.
resultsThe case fatality rate increases with increasing SII. The correlation between SII and 30-day all-cause mortality [hazard ratio (HR) 1.765, 95% confidence interval (CI) 1.330-2.343 (Q3 versus Q1 group)], 365-day all-cause mortality [HR 2.713, 95% CI 2.250-3.272 (Q3 versus Q1 group), HR 1.603, 95% CI 1.312-1.959 (Q3 vs. Q1 group)], congestive heart failure [odds ratio (OR) 1.255, 95% CI 1.006-1.565 (Q2 vs. Q1 group), OR 1.565, 95% CI 1.220-2.009 (Q3 vs. Q1 group)] and cardiogenic shock [OR 1.930. 95% CI 1.271-2.974 (Q2 vs. Q1 group)] were all validated. According to subgroup analysis, individuals who had chosen to have CABG surgery had a stronger correlation between SII and a worse outcome. According to Kaplan-Meier (K-M) survival curves, patients in the Q3 group with SII had the highest rates of morbidity and death. The RCS curves demonstrated an essentially linear connection between SII and 30 days, 365 days, and congestive heart failure even after controlling for covariates.
conclusionsSII was substantially correlated with 30-day all-cause mortality, 365-day all-cause mortality, in-hospital congestive heart failure, and cardiogenic shock in patients who had both hypertension and acute myocardial infarction. In individuals with acute myocardial infarction and hypertension, a greater SII would be regarded as an independent risk factor for a higher death rate.
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