SynthesisLasers in medical science2025
The effect of photobiomodulation therapy on fracture healing: a systematic review and meta-analysis of animal studies.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Heterologous Fibrin Biopolymer as a Key Scaffold for Bone Regeneration: Synergistic Effects with Photobiomodulation and Membrane Therapy.Gels (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review and meta-analysis aimed to evaluate the impact of photobiomodulation therapy (PBMT) on fracture healing in animal models. Following PRISMA guidelines, an electronic search was conducted in PubMed/MEDLINE, Scopus, Embase, and Web of Science databases without date or language restrictions. Animal studies evaluating the effect of PBMT on the healing of complete fractures were included. SYRCLE's risk of bias assessment tool was used for quality appraisal. Meta-analysis and sensitivity analysis were performed for selected outcome measures using Stata version 16, with a significance level of 0.05. Of 1,656 studies, 27 met eligibility criteria. Rabbits and rats were used in 17 and 10 studies, respectively. The tibia was the most common site of fracture, followed by the femur, mandible, and radius. The most frequently used emitters were 780 nm LASER, followed by 808 nm and 830 nm LASER. LEDs were used in comparison to LASERs in three studies and solely in one study. The most frequent energy density and power density were 4 J/cm
Indexed as
Identifiers
40016554What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.