ArticleNature microbiology2025
One-carbon fixation via the synthetic reductive glycine pathway exceeds yield of the Calvin cycle.
Article in Nature microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Toward Solar-Powered Growth of AutotrophicJournal of the American Chemical Society · 2026Article
- FormatotrophicSynthetic and systems biotechnology · 2026Article
- Engineering and Biological Mechanisms of Microalgal COMicroorganisms · 2026Review
- Contribution of C1 Biotechnology to the Achievement of the United Nations' Sustainable Development Goals.Bioengineering (Basel, Switzerland) · 2026Review
- Electrocatalytic COChemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Biosynthesis of Glycine from One-Carbon Resources Using an EngineeredMicroorganisms · 2026Article
- Harnessing plant agriculture to mitigate climate change: A framework to evaluate synthetic biology (and other) interventions.Plant physiology · 2025Article
- A blueprint for designing the next-generation of synthetic CNature communications · 2025Review
- Synthetic CmBio · 2025Article
- Fast growth and high-titer bioproduction from renewable formate via metal-dependent formate dehydrogenase in Escherichia coli.Nature communications · 2025Article
- System-level characterization of engineered and evolved formatotrophicSynthetic and systems biotechnology · 2025Article
- Design and implementation of aerobic and ambient CONature communications · 2025Article
- Surpassing natural limits in one-carbon assimilation.Nature microbiology · 2025Article
- Cell-Free Systems to Mimic and Expand Metabolism.ACS synthetic biology · 2025Review
- Seven critical challenges in synthetic one-carbon assimilation and their potential solutions.FEMS microbiology reviews · 2025Review
- Enzymatic Conversion of COChemical reviews · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
One-carbon feedstocks such as formate could be promising renewable substrates for sustainable microbial production of food, fuels and chemicals. Here we replace the native energy-inefficient Calvin-Benson-Bassham cycle in Cupriavidus necator with the more energy-efficient reductive glycine pathway for growth on formate and CO
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.